2. Inhibitory Antibodies
  3. Rocatinlimab

Rocatinlimab  (Synonyms: AMG 451; KHK4083)

Cat. No.: HY-P99955 Purity: 98.81%
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Rocatinlimab (AMG 451) (KHK4083) is a fully human, non-fucosylated, immunoglobulin G1 (IgG1) anti-OX40 monoclonal antibody. Rocatinlimab can be used for the research of atopic dermatitis (AD).

For research use only. We do not sell to patients.

CAS No. : 2431972-52-8

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1 mg USD 350 In-stock
5 mg USD 910 In-stock
10 mg USD 1450 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

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Description

Rocatinlimab (AMG 451) (KHK4083) is a fully human, non-fucosylated, immunoglobulin G1 (IgG1) anti-OX40 monoclonal antibody. Rocatinlimab can be used for the research of atopic dermatitis (AD)[1].

Isotype

Human IgG1 kappa
Recommend Isotype Controls
Species

Human
Clinical Trial
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Rocatinlimab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
Biological Activity
  • Loaded OX40/TNFRSF4 Protein, Human (HEK293, Fc, HY-P70813) on SA biosensor, can bind Rocatinlimab with an affinity constant of 3.012E-10 M as determined in BLI assay.
  • Immobilized Human OX40/TNFRSF4 Protein (ECD, His Tag) can bind Rocatinlimab. The EC50 for this effect is 2.003 ng/mL.
Purity & Documentation
References
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Rocatinlimab Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rocatinlimab2431972-52-8AMG 451 KHK4083AMG451AMG-451KHK4083KHK 4083KHK-4083Othersimmunoglobulin G1 (IgG1)OX40monoclonal antibodyatopic dermatitis (AD)Inhibitorinhibitorinhibit

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