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E3 ligase Ligand 59

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-173378
    E3 ligase Ligand 59

    		Ligands for E3 Ligase Cancer
    E3 ligase Ligand 59 (Compound 20e) is the E3 ubiquitin ligase ligand of FDU73 (HY-173125). E3 ligase Ligand 59 can be used to synthesize PROTACs .
    E3 ligase Ligand 59
  • HY-173125
    FDU73

    		PROTACs Btk Cancer
    FDU73 is a highly effective and selective BTK PROTAC degrader with a DC50 of 2.9 nM (in JeKo-1 cells). FDU73 can inhibit the proliferation of tumor cells and exhibits anti-tumor activity . (Pink: BTK ligand-14 (HY-173126); Black: Linker (HY-168297); Blue: E3 ligase ligand 59 (HY-173378); E3 ligase ligand+Linker (HY-173127))
    FDU73

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