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GGTI-298

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By Targets:	Apoptosis (2)
By Research Areas:	Cancer (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

GGTI298 Trifluoroacetate 5 Publications Verification	Apoptosis	Cancer
GGTI298 Trifluoroacetate is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, which can inhibit Rap1A with IC₅₀ of 3 μM; little effect on Ha-Ras with IC₅₀ of >20 μM.

*GGTI298*	Apoptosis	Cancer
GGTI298 is a CAAZ peptidomimetic geranylgeranyltransferase I (GGTase I) inhibitor, strongly inhibiting the processing of geranylgeranylated Rap1A with little effect on processing of farnesylated Ha-Ras, with IC₅₀ values of 3 and > 20 μM in vivo, respectively.

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