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GNE1858

" in MedChemExpress (MCE) Product Catalog:

By Targets:	MAP4K (1)
By Research Areas:	Inflammation/Immunology (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*GNE-1858* 2 Publications Verification	MAP4K	Inflammation/Immunology
GNE-1858 is a potent and ATP-competitive hematopoietic progenitor kinase-1 (HPK1) inhibitor, with IC₅₀s of 1.9 nM, 1.9 nM, and 4.5 nM for wild-type and the active mimetic mutants HPK1-TSEE and HPK1-SA, respectively .

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