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Gelsemium elegans

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bcl-2 Family (2) Wnt (1) β-catenin (1)
By Research Areas:	Cancer (5) Inflammation/Immunology (3) Neurological Disease (3)

18

Inhibitors & Agonists

14

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

(Z)-Akuammidine 19-(Z)-Akuammidine; (Z)-Rhazine	Others	Others
(Z)-Akuammidine ((Z)-Rhazine) is isolated from Gelsemium elegans .

16-Epivoacarpine 16-epi-Voacarpine	Others	Others
16-Epivoacarpine is a natural alkaloid isolated from Gelsemium elegans .

Gelsemine	Others	Neurological Disease
Gelsemine, an alkaloid from the Chinese herb Gelsemium elegans, is effective in mitigating chronic pain. Antinociceptive effects.

Koumidine	Others	Others
Koumidine is an alkaloid that can be isolated from Gelsemium elegans .

N-Methoxyanhydrovobasinediol	Others	Others
N-Methoxyanhydrovobasinediol is an alkaloid that can be isolated from Gelsemium elegans. N-Methoxyanhydrovobasinediol can be used as a reference .

11-Hydroxyrankinidine	Others	Others
11-Hydroxyrankinidine is an alkaloid compound isolated from the whole plant of Gelsemium elegans .

11-Hydroxyhumantenine N-Methyl-11-hydroxyrankinidine	Others	Others
11-Hydroxyhumantenine is an alkaloid compound isolated from the EtOH extract of the stems of Gelsemium elegans .

Sempervirine nitrate	Wnt β-catenin	Cancer
Sempervirine is an alkaloid derived from Gelsemium elegans Benth.. Sempervirine inhibits the proliferation of hepatocellular carcinoma (HCC) cells and induces apoptosis by regulating Wnt/β-catenin pathway .

Humantenine	Others	Others
Humantenine is a indole alkaloid compound isolated from Gelsemium elegans .

Koumine N-oxide	Others	Others
Koumine N-oxide is an alkaloid compound isolated from the herb **Gelsemium elegans** .

Uncarinic acid E	Others	Cancer
Uncarinic acid E is a compound can be isolated from Gelsemium elegans BENTH and has anti-tumor activity .

Gelsempervine A 16-epi-Nb-Methylvoacarpine	Others	Others
Gelsempervine A (16-epi-Nb-Methylvoacarpine) is a natural product that can be isolated from Gelsemium elegans .

Humantenmine Gelsenicine	Others	Inflammation/Immunology
Humantenmine, a newalkaloid isolated from Gelsemium elegan Banth in China, has the potential for pain and rheumatic arthritis treatment .

11-Hydroxygelsenicine	Others	Others
11-Hydroxygelsenicine is a 11-hydroxy-substituted gelsedine-type indole alkaloid compound isolated from the EtOH extract of the stems of Gelsemium elegans .

Gelsemine (Standard)	Others	Neurological Disease
Gelsemine (Standard) is the analytical standard of Gelsemine. This product is intended for research and analytical applications. Gelsemine, an alkaloid from the Chinese herb Gelsemium elegans, is effective in mitigating chronic pain. Antinociceptive effects.

Gelsevirine	Others	Neurological Disease Cancer
Gelsevirine is the major alkaloid in Gelsemium elegans with potent anxiolytic effects. The anxiolytic mechanism of Gelsevirine may be involved in the agonist action of the glycine receptor in the brain. Gelsevirine has anti-proliferation activity with IC₅₀ values of 1.41 mM and 1.22 mM for SW480 cells and MGC80-3 cells, respectively .

Koumine	Bcl-2 Family	Inflammation/Immunology Cancer
Koumine is an alkaloid separated from Gelsemium elegans, shows potent anti-tumor activity. Koumine up-regulates the Bax/Bcl-2 ratio and caspase-3 expression in human breast cancer cells . Koumine has anxiolytic, antistress, antipsoriatic, and analgesic activities , protects against the development of arthritis in Rheumatoid arthritis (RA) animal models .

Koumine (Standard)	Bcl-2 Family	Inflammation/Immunology Cancer
Koumine (Standard) is the analytical standard of Koumine. This product is intended for research and analytical applications. Koumine is an alkaloid separated from Gelsemium elegans, shows potent anti-tumor activity. Koumine up-regulates the Bax/Bcl-2 ratio and caspase-3 expression in human breast cancer cells . Koumine has anxiolytic, antistress, antipsoriatic, and analgesic activities , protects against the development of arthritis in Rheumatoid arthritis (RA) animal models .

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