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HDAC3/BRD4-IN-1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-170841
    HDAC3/BRD4-IN-1

    		HDAC Epigenetic Reader Domain Cancer
    HDAC3/BRD4-IN-1 (compound 26n) is an inhibitor of HDAC3/BRD4 with an IC50 of 8 nM for HDAC3 (IC50s are 220 nM and 120 nM for HDAC1 and HDAC2, respectively). HDAC3/BRD4-IN-1 has anti-tumor and anti-proliferative effects by upregulating Ac-H3 and downregulating c-Myc. The half-life of HDAC3/BRD4-IN-1 in human liver microsomes is 29.36 min .
    HDAC3/BRD4-IN-1

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