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Has2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	HIV (1) Isotope-Labeled Compounds (1) Melatonin Receptor (3) Small Interfering RNA (siRNA) (1)
By Research Areas:	Endocrinology (3) Infection (1) Neurological Disease (3)
Oligonucleotides:	Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

Tasimelteon BMS-214778; VEC-162	Melatonin Receptor	Neurological Disease Endocrinology
Tasimelteon (BMS-214778) is an orally active and selective dual melatonin receptor agonist (DMRA). Tasimelteon has 2.1-4.4 times greater affinity for the MT2 receptor than for the MT1 receptor. Tasimelteon is a circadian regulator and has the potential for Non-24-Hour Sleep-Wake Disorder (Non-24) ^[2].

HAS2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
HAS2 Human Pre-designed siRNA Set A contains three designed siRNAs for HAS2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HAS2 Human Pre-designed siRNA Set A HAS2 Human Pre-designed siRNA Set A

Tasimelteon-d5 BMS-214778-d₅; VEC-162-d₅	Isotope-Labeled Compounds Melatonin Receptor	Neurological Disease Endocrinology
Tasimelteon-d₅ is the deuterium labeled Tasimelteon. Tasimelteon (BMS-214778) is an orally active and selective dual melatonin receptor agonist (DMRA). Tasimelteon has 2.1-4.4 times greater affinity for the MT2 receptor than for the MT1 receptor. Tasimelteon is a circadian regulator and has the potential for Non-24-Hour Sleep-Wake Disorder (Non-24)[1][2].

Tasimelteon (Standard)	Melatonin Receptor	Neurological Disease Endocrinology
Tasimelteon (Standard) is the analytical standard of Tasimelteon. This product is intended for research and analytical applications. Tasimelteon (BMS-214778) is an orally active and selective dual melatonin receptor agonist (DMRA). Tasimelteon has 2.1-4.4 times greater affinity for the MT2 receptor than for the MT1 receptor. Tasimelteon is a circadian regulator and has the potential for Non-24-Hour Sleep-Wake Disorder (Non-24) ^[2].

L 738372	HIV	Infection
L-738372 is a non-competitive reversible inhibitor of HIV-1 reverse transcriptase (RT) with an inhibition constant (K_i) of 140 nM against dTTP. When combined with any nucleoside analogs (such as azidothymidine triphosphate, didexoyinosine triphosphate, or didexoycytidine triphosphate), L-738372 exhibits synergistic inhibition of RT activity. L-738372 has 2-3 times more inhibitory potency against the azidothymidine-resistant RT (D67N, K70R, T215Y, K219Q) compared to the wild-type RT. L-738372 holds promise for research in the field of HIV virus treatment .

Cat. No.	Compare	Product Name	Species	Source

	HAS2 Protein, Mouse (His) Has2; Hyaluronan syntHase 2; EC 2.4.1.212; Hyaluronate syntHase 2; Hyaluronic acid syntHase 2; HA syntHase 2	Mouse	E. coli
	The HAS2 protein adds GlcNAc or GlcUA monosaccharides to hyaluronic acid, playing a crucial role in its synthesis. HAS2 Protein, Mouse (His) is the recombinant mouse-derived HAS2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of HAS2 Protein, Mouse (His) is 308 a.a., with molecular weight of ~39.9 kDa.

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Cat. No.	Product Name	Chemical Structure

Tasimelteon-d5
Tasimelteon-d₅ is the deuterium labeled Tasimelteon. Tasimelteon (BMS-214778) is an orally active and selective dual melatonin receptor agonist (DMRA). Tasimelteon has 2.1-4.4 times greater affinity for the MT2 receptor than for the MT1 receptor. Tasimelteon is a circadian regulator and has the potential for Non-24-Hour Sleep-Wake Disorder (Non-24)[1][2].

HAS2 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
HAS2 Human Pre-designed siRNA Set A contains three designed siRNAs for HAS2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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