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ITI-007-d<sub>4</sub>

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Dopamine Receptor (1) Isotope-Labeled Compounds (1)
By Research Areas:	Cancer (1) Neurological Disease (1)

Targets Recommended: P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-17637S2

Lumateperone-d4 ITI-007-d<sub>4sub>	Isotope-Labeled Compounds Dopamine Receptor 5-HT Receptor	Neurological Disease Cancer
Lumateperone-d₄ (ITI-007-d₄) is deuterium labeled Lumateperone. Lumateperone (ITI-007) is an orally active 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a dopamine D1 receptor modulator. Lumateperone has anticancer activity and can also be used for the study of schizophrenia and bipolar depression .

Cat. No.	Product Name	Chemical Structure

HY-17637S2

Lumateperone-d4
Lumateperone-d₄ (ITI-007-d₄) is deuterium labeled Lumateperone. Lumateperone (ITI-007) is an orally active 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a dopamine D1 receptor modulator. Lumateperone has anticancer activity and can also be used for the study of schizophrenia and bipolar depression .

Lumateperone-d4

Lumateperone-d₄ (ITI-007-d₄) is deuterium labeled Lumateperone. Lumateperone (ITI-007) is an orally active 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a dopamine D1 receptor modulator. Lumateperone has anticancer activity and can also be used for the study of schizophrenia and bipolar depression .

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ITI-007-d<sub>4</sub>

Inhibitors & Agonists

Isotope-Labeled Compounds