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ITK degrader2

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-153322
    ITK degrader 2

    		PROTACs Itk Cancer
    ITK degrader 2 (compound 30) is an orally active, PROTAC-based ITK-targeted degrader (DC50<10 nM). ITK degrader 2 exhibits Cmax and Tmax in mice (po; 90 mg/kg) of 0.87 μM and 2 h, respectively. At this dose, ITK degrader 2 degrades ITK by 20% (6 h) in mice .
    ITK degrader 2

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