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Results for "

Inositol triphosphate receptor

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Natural
Products

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-163171
    ARN11391

    		Chloride Channel Neurological Disease
    ARN 11391 is a selective enhancer of inositol triphosphate receptor type 1 (ITPR1). ARN 11391 can be used in the study of spinocerebellar ataxia .
    ARN11391
  • HY-17397
    Strontium Ranelate
    2 Publications Verification

    Distrontium renelate; S12911

    		 CaSR Metabolic Disease
    Strontium Ranelate (S12911) is an antiosteoporotic agent that acts by reducing bone resorption and promoting bone formation, thereby inducing a positive bone balance. Strontium Ranelate can also activate the calcium-sensing receptor (CaSR) in non skeletal cells, resulting in the activation of inositol 1, 4, 5-triphosphate production and mitogen-activated protein kinase signaling .
    Strontium Ranelate
  • HY-W009724
    2-Aminoethyl diphenylborinate
    35+ Cited Publications

    2-APB

    		 Calcium Channel TRP Channel CRAC Channel Inflammation/Immunology
    2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of Inositol triphosphate receptor (IP3R). 2-Aminoethyl diphenylborinate also inhibits the store-operated Ca 2+ (SOC) channel and activates some TRP channels (V1, V2 and V3). Additionally, 2-Aminoethyl diphenylborinate has inhibitory effects on vasospasm. At high concentrations, it exhibits specific anti-inflammatory and antioxidant effects in neural tissue .
    2-Aminoethyl diphenylborinate
  • HY-162556
    (+)-Desmethylxestospongin B

    (+)-dmXeB

    		 Apoptosis Cancer
    (+)-Desmethylxestospongin B ((+)-dmXeB) is a potent antagonist of inositol triphosphate receptor (IP3R), leading to cellular autophagy and allowing selective tumor cell apoptosis .
    (+)-Desmethylxestospongin B
  • HY-17397R
    Strontium Ranelate (Standard)

    		CaSR Metabolic Disease
    Strontium Ranelate (Standard) is the analytical standard of Strontium Ranelate. This product is intended for research and analytical applications. Strontium Ranelate (S12911) is an antiosteoporotic agent that acts by reducing bone resorption and promoting bone formation, thereby inducing a positive bone balance. Strontium Ranelate can also activate the calcium-sensing receptor (CaSR) in non skeletal cells, resulting in the activation of inositol 1, 4, 5-triphosphate production and mitogen-activated protein kinase signaling .
    Strontium Ranelate (Standard)

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