2. Membrane Transporter/Ion Channel
  3. Chloride Channel
  4. ARN11391

ARN 11391 is a selective enhancer of inositol triphosphate receptor type 1 (ITPR1). ARN 11391 can be used in the study of spinocerebellar ataxia.

For research use only. We do not sell to patients.

ARN11391 Chemical Structure

ARN11391 Chemical Structure

CAS No. : 1214569-31-9

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1 mg USD 65 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

ARN 11391 is a selective enhancer of inositol triphosphate receptor type 1 (ITPR1). ARN 11391 can be used in the study of spinocerebellar ataxia[1].

Molecular Weight

383.48

Formula

C22H29N3O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=C2C(CCCC2)=NN1CC)NC3=C(OCC4OCCCC4)C=CC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 38.35 mg/mL (100.01 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6077 mL 13.0385 mL 26.0770 mL
5 mM 0.5215 mL 2.6077 mL 5.2154 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6077 mL 13.0385 mL 26.0770 mL 65.1924 mL
5 mM 0.5215 mL 2.6077 mL 5.2154 mL 13.0385 mL
10 mM 0.2608 mL 1.3038 mL 2.6077 mL 6.5192 mL
15 mM 0.1738 mL 0.8692 mL 1.7385 mL 4.3462 mL
20 mM 0.1304 mL 0.6519 mL 1.3038 mL 3.2596 mL
25 mM 0.1043 mL 0.5215 mL 1.0431 mL 2.6077 mL
30 mM 0.0869 mL 0.4346 mL 0.8692 mL 2.1731 mL
40 mM 0.0652 mL 0.3260 mL 0.6519 mL 1.6298 mL
50 mM 0.0522 mL 0.2608 mL 0.5215 mL 1.3038 mL
60 mM 0.0435 mL 0.2173 mL 0.4346 mL 1.0865 mL
80 mM 0.0326 mL 0.1630 mL 0.3260 mL 0.8149 mL
100 mM 0.0261 mL 0.1304 mL 0.2608 mL 0.6519 mL
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ARN11391 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ARN113911214569-31-9ARN 11391ARN-11391Chloride ChannelCl− ChannelsCalcium signalingInositol triphosphate receptorSpinocerebellar ataxiaInhibitorinhibitorinhibit

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