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Results for "

KARI

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-153351
    IpOHA

    		Bacterial Infection
    IpOHA is a potent plant KARI inhibitor. IpOHA also is an antimycobacterial agent with a Ki value of 97.7 nM for Mycobacterium tuberculosis (Mt) .
    IpOHA
  • HY-146298
    Mt KARI-IN-1

    		Bacterial Infection
    Mt KARI-IN-1 (Lead compound) is a potent Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI) inhibitor with a Ki value of 3.06 μM .
    Mt KARI-IN-1
  • HY-146299
    Mt KARI-IN-2

    		Bacterial Infection
    Mt KARI-IN-2 (compound 5b) is a potent Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI) inhibitor with a Ki value of 2.02 μM. Mt KARI-IN-2 has inhibitory activity against Mtb H37Rv (MIC = 0.78 μM) and low cytotoxicity (HEK IC50 > 86 μg/mL) .
    Mt KARI-IN-2
  • HY-146300
    Mt KARI-IN-4

    		Bacterial Infection
    Mt KARI-IN-4 (compound 5c) is a potent Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI) inhibitor with a Ki value of 5.48 μM. Mt KARI-IN-4 has inhibitory activity against Mtb H37Rv (MIC = 0.78 μM) and low cytotoxicity (HEK IC50 > 72 μg/mL) .
    Mt KARI-IN-4
  • HY-146301
    Mt KARI-IN-5

    		Bacterial Infection
    Mt KARI-IN-5 (compound 6c) is a potent Mycobacterium tuberculosis ketol-acid reductoisomerase (Mtb KARI) inhibitor with a Ki value of 4.72 μM. Mt KARI-IN-5 has inhibitory activity against Mtb H37Rv (MIC = 1.56 μM) and low cytotoxicity (HEK IC50 > 64 μg/mL)
    Mt KARI-IN-5

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