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Results for "

KDM3B

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Recombinant Proteins

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-162301
    P3FI-63

    		Histone Demethylase Cancer
    P3FI-63 is a KDM3B inhibitor with a IC50 value of 7 μM. P3FI-63 has antitumor activity .
    P3FI-63
  • HY-139348
    PFI-90

    		Histone Demethylase Apoptosis Cancer
    PFI-90 is a selective inhibitor of histone demethylase (KDM3B) that inhibits PAX3-FOXO1 action. PFI-90 induces apoptosis and myogenic differentiation, resulting in the cell death increased. PFI-90 has the potential for the antitumor activity. (patent WO2021101929A1).
    PFI-90
  • HY-168593
    PROTAC KDM3 degrader-1

    		β-catenin PROTACs Wnt Histone Demethylase Cancer
    PROTAC KDM3 degrader-1 (Compound 4) is a CRBN-recruiting PROTAC designed based on the IOX1 (HY-12304) scaffold. PROTAC KDM3 degrader-1 selectively degrades the KDM3A and KDM3B proteins, thereby inhibiting the Wnt/β-catenin signaling pathway. PROTAC KDM3 degrader-1 significantly suppresses the self-renewal capacity of colorectal cancer stem cells and inhibits the growth of colorectal cancer tumors. PROTAC KDM3 degrader-1 is suitable for research on colorectal cancer (Target protein ligand (Pink): HY-12304; linker (Black): HY-22335; Conjugate of E3 ligase ligand and linker: HY-112599; E3 ligase (Blue): HY-41547) .
    PROTAC KDM3 degrader-1
  • HY-RS07212
    KDM3B Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    KDM3B Human Pre-designed siRNA Set A contains three designed siRNAs for KDM3B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    KDM3B Human Pre-designed siRNA Set A
    KDM3B Human Pre-designed siRNA Set A

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