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Results for "

KLB

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (1) Caspase (2) Small Interfering RNA (siRNA) (3)
By Research Areas:	Cardiovascular Disease (2) Inflammation/Immunology (1)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

KLB Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
KLB Human Pre-designed siRNA Set A contains three designed siRNAs for KLB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

KLB Human Pre-designed siRNA Set A KLB Human Pre-designed siRNA Set A

Cosdosiran QPI-1007	Small Interfering RNA (siRNA) Caspase	Cardiovascular Disease
Cosdosiran is a chemically modified siRNA designed to temporarily inhibit expression of the caspase 2 protein and can be used for the study of nonarteritic anterior ischemic optic neuropathy and other optic neuropathies such as glaucoma that result in the death of retinal ganglion cells.?

Cosdosiran sodium QPI-1007 sodium	Small Interfering RNA (siRNA) Caspase	Cardiovascular Disease
Cosdosiran sodium is a chemically modified siRNA designed to temporarily inhibit expression of the caspase 2 protein and can be used for the study of nonarteritic anterior ischemic optic neuropathy and other optic neuropathies such as glaucoma that result in the death of retinal ganglion cells.?

IgdE protease	Biochemical Assay Reagents	Inflammation/Immunology
IgdE protease is a cysteine protease, which is initially isolated from Streptococcus agalactiae. IgdE protease digests monoclonal antibodies (mAbs) of the IgG1 type specifically at their upper hinge region, produces Fc/2, hinge peptide dimers, and Fab fragment. IgdE protease can be used in disulfide bonds and free thiol analysis, as it requires no reducing agents for cleavage .

Cat. No.	Compare	Product Name	Species	Source

	Klotho beta Protein, Human (HEK293, His) betaKlotho; beta-klotho; BKL; KLB; klotho beta like; Klotho beta; MGC142213	Human	HEK293
	Klotho beta protein plays a critical role in the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), a key enzyme controlling bile acid synthesis. Although its glycosidase activity may be inactive, Klotho beta enhances the binding ability of FGFR1 and FGFR4 to FGF21, promoting their interaction. Klotho beta Protein, Human (HEK293, His) is the recombinant human-derived Klotho beta protein, expressed by HEK293 , with C-His labeled tag. The total length of Klotho beta Protein, Human (HEK293, His) is 954 a.a., with molecular weight of 112-140 kDa.

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