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Results for "

KOE-1173

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-A0093S
    Mexiletine-d6 hydrochloride

    KOE-1173-d6 (hydrochloride)

    		 Sodium Channel Cardiovascular Disease
    Mexiletine-d6 (hydrochloride) is a deuterium labeled Mexiletine hydrochloride (KOE-1173 hydrochloride). Mexiletine hydrochloride, a Class IB antianhythmic, is a non-selective voltage-gated sodium channel blocker[1].
    Mexiletine-d6 hydrochloride
  • HY-A0093
    Mexiletine hydrochloride
    1 Publications Verification

    KOE-1173 hydrochloride

    		 Sodium Channel Cardiovascular Disease Neurological Disease
    Mexiletine is an orally effective antiarrhythmic agent which has also been found to be effective for myotonia and neuropathic pain. Mexiletine exerts its efficacy through blocking sodium channels (IC50 : 75±8 μM for tonic block, 23.6±2.8 μM for use-dependent block), therefore can be used for cardiovascular and neurological research .
    Mexiletine hydrochloride
  • HY-119521
    Mexiletine

    KOE-1173

    		 Sodium Channel Cardiovascular Disease Neurological Disease
    Mexiletine is an orally effective antiarrhythmic agent which has also been found to be effective for myotonia and neuropathic pain. Mexiletine exerts its efficacy through blocking sodium channels (IC50 : 75±8 μM for tonic block, 23.6±2.8 μM for use-dependent block), therefore can be used for cardiovascular and neurological research .
    Mexiletine
  • HY-A0093S1
    Mexiletine-d3 hydrochloride

    KOE-1173-d3 hydrochloride

    		 Isotope-Labeled Compounds Sodium Channel Cardiovascular Disease
    Mexiletine-d3 (hydrochloride) is deuterium labeled Mexiletine (hydrochloride). Mexiletine hydrochloride (KOE-1173 hydrochloride), a Class IB antianhythmic, is a non-selective voltage-gated sodium channel blocker[1][2].
    Mexiletine-d3 hydrochloride
  • HY-A0093R
    Mexiletine hydrochloride (Standard)

    KOE-1173 hydrochloride (Standard)

    		 Sodium Channel Cardiovascular Disease Neurological Disease
    Mexiletine (hydrochloride) (Standard) is the analytical standard of Mexiletine (hydrochloride). This product is intended for research and analytical applications. Mexiletine is an orally effective antiarrhythmic agent which has also been found to be effective for myotonia and neuropathic pain. Mexiletine exerts its efficacy through blocking sodium channels (IC50 : 75±8 μM for tonic block, 23.6±2.8 μM for use-dependent block), therefore can be used for cardiovascular and neurological research .
    Mexiletine hydrochloride (Standard)

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