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LBH589-d<sub>4</sub>

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

2

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-10224S

    LBH589-d<sub>4sub>; NVP-LBH589-d<sub>4sub>

    HDAC Autophagy HIV Apoptosis Cancer
    Panobinostat-d4 is the deuterium labeled Panobinostat. Panobinostat (LBH589; NVP-LBH589) is a potent and orally active non-selective HDAC inhibitor, and has antineoplastic activities[1][2]. Panobinostat induces HIV-1 virus production even at low concentration range 8-31 nM, stimulates HIV-1 expression in latently infected cells[4]. Panobinostat induces cell apoptosis and autophagy. Panobinostat can be used for the study of refractory or relapsed multiple myeloma[3].
    Panobinostat-d4
  • HY-10224S1

    LBH589-d<sub>4sub> hydrochloride; NVP-LBH589-d<sub>4sub> hydrochloride

    Isotope-Labeled Compounds HDAC Autophagy HIV Apoptosis Cancer
    Panobinostat-d4 (hydrochloride) is deuterium labeled Panobinostat. Panobinostat (LBH589; NVP-LBH589) is a potent and orally active non-selective HDAC inhibitor, and has antineoplastic activities[1][2]. Panobinostat induces HIV-1 virus production even at low concentration range 8-31 nM, stimulates HIV-1 expression in latently infected cells[4]. Panobinostat induces cell apoptosis and autophagy. Panobinostat can be used for the study of refractory or relapsed multiple myeloma[3].
    Panobinostat-d4 hydrochloride

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