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LC3-mHTT-IN-AN2

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-130259
    LC3-mHTT-IN-AN2

    		Atg8/LC3 ATTECs Autophagy Neurological Disease
    LC3-mHTT-IN-AN2 (Compound AN2) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN2 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons .
    LC3-mHTT-IN-AN2

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