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Results for "

LRP5

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Small Interfering RNA (siRNA) (3) Wnt (3)
By Research Areas:	Cancer (2) Cardiovascular Disease (1) Infection (1) Inflammation/Immunology (1)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Recombinant Proteins

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-125146

BMD4503-2	Wnt	Others
BMD4503-2 is a quinoxaline derivative with inhibitory activity against *LRP5/6-sclerostin* interactions. BMD4503-2 restores the activity of the Wnt/β-catenin signaling pathway by competitively binding to the *LRP5/6-sclerostin* complex. BMD4503-2 can be used in the study of Wnt signaling pathways in bone development, maintenance and osteoporosis .

HY-RS16292

Lrp5 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Cancer
Lrp5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lrp5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control. Components Lrp5 siRNA-1: 5 nmol (HPLC) Lrp5 siRNA-2: 5 nmol (HPLC) Lrp5 siRNA-3: 5 nmol (HPLC) siRNA Negative Control: 5 nmol (HPLC) FAM-labeled siRNA Negative Control: 5 nmol (HPLC) GAPDH siRNA Positive Control: 5 nmol (HPLC)

Lrp5 Mouse Pre-designed siRNA Set A

Small Interfering RNA (siRNA)

Cancer

Lrp5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Lrp5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Components

Lrp5 siRNA-1: 5 nmol (HPLC)

Lrp5 siRNA-2: 5 nmol (HPLC)

Lrp5 siRNA-3: 5 nmol (HPLC)

siRNA Negative Control: 5 nmol (HPLC)

FAM-labeled siRNA Negative Control: 5 nmol (HPLC)

GAPDH siRNA Positive Control: 5 nmol (HPLC)

Lrp5 Mouse Pre-designed siRNA Set A Lrp5 Mouse Pre-designed siRNA Set A

HY-RS07800

LRP5 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
LRP5 Human Pre-designed siRNA Set A contains three designed siRNAs for LRP5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

LRP5 Human Pre-designed siRNA Set A LRP5 Human Pre-designed siRNA Set A

HY-169508

BMD4503-1	Wnt	Others
BMD4503-1 is a quinoxaline derivative. BMD4503-1 can inhibit the *LRP5/6-Sclerostin* interaction and regulate the Wnt signaling pathway .

HY-E70390

C1s Enzyme masp-2, c1 esterase, c1-esterase	Wnt	Cardiovascular Disease Inflammation/Immunology
C1s Enzyme is a subunit of the complement C1 complex, which activates the complement as a serine protease. C1s Enzyme cleaves LRP5 and LRP6, and thus activates the Wnt/β-Catenin signaling pathway. C1s Enzyme promotes the macrophage M2 polarization and inhibits M1 polarization. C1s Enzyme enhances efferocytosis, exhibits anti-inflammatory activity .

HY-RS16291

Bnip3 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Infection Cancer
Bnip3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Bnip3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control. Components Bnip3 siRNA-1: 5 nmol (HPLC) Bnip3 siRNA-2: 5 nmol (HPLC) Lrp5 siRNA-3: 5 nmol (HPLC) siRNA Negative Control: 5 nmol (HPLC) FAM-labeled siRNA Negative Control: 5 nmol (HPLC) GAPDH siRNA Positive Control: 5 nmol (HPLC)

Bnip3 Mouse Pre-designed siRNA Set A

Small Interfering RNA (siRNA)

Infection Cancer

Bnip3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Bnip3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Components

Bnip3 siRNA-1: 5 nmol (HPLC)

Bnip3 siRNA-2: 5 nmol (HPLC)

Lrp5 siRNA-3: 5 nmol (HPLC)

siRNA Negative Control: 5 nmol (HPLC)

FAM-labeled siRNA Negative Control: 5 nmol (HPLC)

GAPDH siRNA Positive Control: 5 nmol (HPLC)

Bnip3 Mouse Pre-designed siRNA Set A Bnip3 Mouse Pre-designed siRNA Set A

Cat. No.	Compare	Product Name	Species	Source

HY-P77989

	LRP-5 Protein, Human (HEK293, mFc) LRP-5; LRP-7; LR3; BMND1; BMND1OPTA1; EVR1; EVR4; HBM; LR3VBCH2; LRP5; LRP7; OPPG; OPS; OPTA1; VBCH2	Human	HEK293
	The LRP-5 protein functions as a coreceptor, cooperating with Frizzled receptors to initiate the canonical Wnt signaling pathway. It is critical for cell fate determination and self-renewal and plays an important role in posterior ectoderm patterning during gastrulation and bone development by affecting osteoblast proliferation and differentiation. LRP-5 Protein, Human (HEK293, mFc) is the recombinant human-derived LRP-5 protein, expressed by HEK293 , with C-mFc labeled tag. The total length of LRP-5 Protein, Human (HEK293, mFc) is 620 a.a., with molecular weight of 110-115 kDa.

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LRP5 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
LRP5 Human Pre-designed siRNA Set A contains three designed siRNAs for LRP5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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