Search Result

Results for "

LRP5

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Small Interfering RNA (siRNA) (1) Wnt (1)
By Research Areas:	Cardiovascular Disease (1) Inflammation/Immunology (1)
Oligonucleotides:	Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

LRP5 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
LRP5 Human Pre-designed siRNA Set A contains three designed siRNAs for LRP5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

LRP5 Human Pre-designed siRNA Set A LRP5 Human Pre-designed siRNA Set A

BMD4503-2	Others	Others
BMD4503-2 is a quinoxaline derivative with inhibitory activity against *LRP5/6-sclerostin* interactions. BMD4503-2 restores the activity of the Wnt/β-catenin signaling pathway by competitively binding to the *LRP5/6-sclerostin* complex. BMD4503-2 can be used in the study of Wnt signaling pathways in bone development, maintenance and osteoporosis .

C1s Enzyme masp-2, c1 esterase, c1-esterase	Wnt	Cardiovascular Disease Inflammation/Immunology
C1s Enzyme is a subunit of the complement C1 complex, which activates the complement as a serine protease. C1s Enzyme cleaves LRP5 and LRP6, and thus activates the Wnt/β-Catenin signaling pathway. C1s Enzyme promotes the macrophage M2 polarization and inhibits M1 polarization. C1s Enzyme enhances efferocytosis, exhibits anti-inflammatory activity .

Cat. No.	Compare	Product Name	Species	Source

	LRP-5 Protein, Human (HEK293, mFc) LRP-5; LRP-7; LR3; BMND1; BMND1OPTA1; EVR1; EVR4; HBM; LR3VBCH2; LRP5; LRP7; OPPG; OPS; OPTA1; VBCH2	Human	HEK293
	LRP-5 Protein functions as a coreceptor, collaborating with frizzled receptors to initiate the canonical Wnt signaling pathway. It crucially regulates cell fate determination, self-renewal, and plays a significant role in posterior epiblast patterning during gastrulation and bone development by influencing osteoblast proliferation and differentiation. LRP-5 facilitates the formation of a signaling complex, stabilizing beta-catenin and activating TCF/LEF-mediated transcription. As a coreceptor for non-Wnt proteins like norrin/NDP, LRP-5 contributes to retinal vascular development. Interactions with partners, including FZD8, AXIN1, DKK1, MESD, KREMEN2, CSNK1E, SOST, APCDD1, and CAPRIN2, underscore its intricate involvement in diverse cellular processes. LRP-5 Protein, Human (HEK293, mFc) is the recombinant human-derived LRP-5 protein, expressed by HEK293, with C-mFc labeled tag. The total length of LRP-5 Protein, Human (HEK293, mFc) is 620 a.a., with molecular weight of 110-115 kDa.

Compare Products


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

LRP5 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
LRP5 Human Pre-designed siRNA Set A contains three designed siRNAs for LRP5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Name
Email *

	Sorry, but the email address you supplied was invalid.