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LWG 301

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Glutaminase (1)
By Research Areas:	Cancer (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*LWG-301*	Glutaminase Apoptosis	Cancer
LWG-301 is an allosteric inhibitor of Glutaminase 1 (GLS1) with an IC₅₀ value of 7 nM. LWG-301 significantly block glutamine metabolism, increases intracellular ROS, thus induces apoptosis. LWG-301 exhibits moderate antitumor effects in HCT116 xenograft model .

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