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LolCDE

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-130839
    LolCDE-IN-1

    		Bacterial Infection
    LolCDE-IN-1 is an inhibitor of the Lol proteins (LolCDE) complex, with antibacterial activity .
    LolCDE-IN-1
  • HY-124658
    G0507

    		Bacterial Infection
    G0507, a pyrrolopyrimidinedione compound, is a potent LolCDE ABC Transporter inhibitor. G0507 is a inhibitor of Escherichia coli growth and induces the extracytoplasmic σE stress response. G0507 acts as a chemical probe to dissect lipoprotein trafficking in Gram-negative bacteria .
    G0507
  • HY-130840
    LolCDE-IN-2

    		Bacterial Cancer
    LolCDE-IN-2 is a potent Lol protein (LolCDE) inhibitor. LolCDE-IN-2 inhibits E. coli MG1655 with a MIC of 2 μg/ml. Antibacterial activity .
    LolCDE-IN-2
  • HY-136802
    LolCDE-IN-3

    		Others Infection
    LolCDE-IN-3 (compound 8) is a LolCDE inhibitor with antibacterial activity.
    LolCDE-IN-3
  • HY-126463
    LolCDE-IN-4

    		Bacterial Infection
    LolCDE-IN-4 (Compound 1) is exhibits antibacterial efficacy against gram negative bacteria Escherichia coli (MIC of 0.25-32 µg/ml) and Haemophilus influenzae, through inhibition LolCDE complex and disruption of lipoproteins release from the inner membrane .
    LolCDE-IN-4

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