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Results for "

MAX

" in MedChemExpress (MCE) Product Catalog:

41

Inhibitors & Agonists

3

Screening Libraries

7

Fluorescent Dye

1

Biochemical Assay Reagents

3

Peptides

8

Natural
Products

4

Recombinant Proteins

5

Antibodies

2

Click Chemistry

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-145723

    FLT3 FGFR Inflammation/Immunology Cancer
    MAX-40279 is a dual and potent inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 has the potential for the research of acute myelogenous leukemia (AML) (extracted from patent WO2021180032) .
    MAX-40279
  • HY-145723B

    FLT3 FGFR Inflammation/Immunology Cancer
    MAX-40279 hemifumarate is a dual and potent inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 hemifumarate has the potential for the research of acute myelogenous leukemia (AML) (extracted from patent WO2021180032) .
    MAX-40279 hemifumarate
  • HY-145723C

    FLT3 FGFR Inflammation/Immunology Cancer
    MAX-40279 hemiadipate is a dual and potent inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 hemiadipate has the potential for the research of acute myelogenous leukemia (AML) (extracted from patent WO2021180032) .
    MAX-40279 hemiadipate
  • HY-153064

    PD-1/PD-L1-IN-30

    PD-1/PD-L1 Cancer
    MAX-10181 (PD-1/PD-L1-IN-30) is a PD-1/PD-L1 binding inhibitor, with an IC50 value of 0.018 μM. MAX-10181 can be used for research of cancers and other related diseases .
    MAX-10181
  • HY-134975

    c-Myc Cancer
    NY2267 is a disruptor of Myc-Max interaction, with an IC50 of 36.5 μM. NY2267 inhibits Myc- and Jun-induced transcriptional activation .
    NY2267
  • HY-100669
    Mycro 3
    5 Publications Verification

    c-Myc Autophagy Cancer
    Mycro 3 is an orally active, potent and selective inhibitor of Myc-associated factor X (MAX) dimerization. Mycro 3 also inhibit DNA binding of c-Myc . Mycro 3 could be used for the research of pancreatic cancer .
    Mycro 3
  • HY-145723A

    FLT3 FGFR Inflammation/Immunology Cancer
    MAX-40279 hydrochloride is a dual and potent inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 hydrochloride has the potential for the research of acute myelogenous leukemia (AML) (extracted from patent WO2021180032) .
    MAX-40279 hydrochloride
  • HY-P10699

    Biochemical Assay Reagents Others
    MAX1 is a self-assembling peptide used to prepare hydrogels .
    MAX1
  • HY-RS08177

    Small Interfering RNA (siRNA) Others

    MAX Human Pre-designed siRNA Set A contains three designed siRNAs for MAX gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    MAX Human Pre-designed siRNA Set A
    MAX Human Pre-designed siRNA Set A
  • HY-N4074

    Others Others
    6"-O-Malonylglycitin is an isoflavone glycoside that can be isolated from Glycine max .
    6
  • HY-N7273

    Apoptosis Cancer
    Soyasaponin III, a monodesmodic oleanane triterpenoid, is one of the main potentially bioactive saponins found in soy (Glycine max) and related products. Soyasaponin III can induce apoptosis in Hep-G2 cells .
    Soyasaponin III
  • HY-136784

    Fluorescent Dye Others
    Rhod-2 (potassium salt) is a water-soluble, red fluorescent calcium indicator. It exhibits a significant shift in fluorescence intensity upon calcium binding (ex max=549 nm; calcium-free v. ex/em max=552/581 nm; calcium-bound). Unlike the UV-excitable indicators fura-2 and indo-1 (HY-D0121), there is no accompanying spectral shift.
    Rhod-2 potassium
  • HY-N6999

    Others Metabolic Disease
    Soyasaponin Ac is a triterpenoid isolated from the seeds of Glycine max.
    Soyasaponin Ac
  • HY-147291

    c-Myc PARP Apoptosis Cancer
    VPC-70063 is a potent Myc-Max inhibitor with an IC50 value of 8.9 μM for Myc-Max transcriptional activity inhibition. VPC-70063 reduces UBE2C promotor activity and AR-V7 levels, and induces PARP cleavage. VPC-70063 induces apoptosis and blocks Myc-Max interactions with DNA. VPC-70063 can be used for researching anticancer .
    VPC-70063
  • HY-125636

    Others Cancer
    Mycro1 is an inhibitor of c-Myc/Max dimer and DNA binding, with an IC50 value of 30 μM for the inhibition of Myc/Max DNA binding activity. Mycro1 can inhibit c-myc-dependent cell proliferation, gene transcription and oncogenic transformation .
    Mycro1
  • HY-126979

    Others Cancer
    Mycro2 is an inhibitor of c-Myc/Max dimer and DNA binding, with an IC50 value of 23 μM for the inhibition of Myc/Max DNA binding activity. Mycro2 can inhibit c-myc-dependent cell proliferation, gene transcription and oncogenic transformation .
    Mycro2
  • HY-100996
    10074-G5
    2 Publications Verification

    c-Myc Autophagy Cancer
    10074-G5 is an inhibitor of c-Myc-Max dimerization with an IC50 of 146 μM.
    10074-G5
  • HY-N12273

    Acetyl-soyasaponin A5

    Others Others
    Soyasaponin Ae (Acetyl-soyasaponin A5) can be isolated from the seeds of Glycine max MERRILL .
    Soyasaponin Ae
  • HY-122683
    sAJM589
    1 Publications Verification

    c-Myc Cancer
    sAJM589 is a Myc inhibitor which potently disrupts the Myc-Max heterodimer with an IC50 of 1.8 μM .
    sAJM589
  • HY-125978

    c-Myc Cancer
    JY-3-094 is a Myc inhibitor that inhibits Myc-Max heterodimer formation (IC50: 33 μM) .
    JY-3-094
  • HY-130736

    JF549, SE; JF549, NHS

    Fluorescent Dye Others
    Janelia Fluor® 549, SE (JF549, SE) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
    Janelia Fluor® 549, SE
  • HY-131022

    JF549 TFA

    Fluorescent Dye Others
    Janelia Fluor® 549 TFA (JF549 TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
    Janelia Fluor® 549 TFA
  • HY-131024

    JF549, Tetrazine

    Fluorescent Dye Others
    Janelia Fluor® 549, Tetrazine (JF549, Tetrazine) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
    Janelia Fluor® 549, Tetrazine
  • HY-131023

    JF549, Maleimide TFA

    Fluorescent Dye Others
    Janelia Fluor® 549, Maleimide TFA (JF549, Maleimide TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
    Janelia Fluor® 549, Maleimide TFA
  • HY-150259

    PROTACs c-Myc Cancer
    MDEG-541 is a potent MYC-MAX degrader. MDEG-541 is a PROTAC that based on the MYC-MAX dimerization inhibitor 10058-F4 derivative 28RH and Thalidomide (HY-14658). MDEG-541 shows antiproliferative activity. MDEG-541 decreases the expression of GSPT1, MYC, GSPT2, PLK1 protein .
    MDEG-541
  • HY-12702
    10058-F4
    Maximum Cited Publications
    38 Publications Verification

    c-Myc Autophagy Cancer
    10058-F4 is a c-Myc inhibitor that prevents c-Myc-Max dimerization and transactivation of c-Myc target gene expression.
    10058-F4
  • HY-115839A

    Detajmium bitartrate; Tachmalcor

    Others Cardiovascular Disease
    Detajmium (L-tartrate) is an antiarrhythmic compound. Detajmium has effect on V max in both dog ventricular muscle and Purkinje fibers was frequency dependent .
    Detajmium L-tartrate
  • HY-N6878

    NO Synthase Inflammation/Immunology
    Cauloside D is a triterpene glycoside isolated from Caulophyllum robustum Max. Cauloside D exerts anti-inflammatory effects through the inhibition of expression of iNOS and proinflammatory cytokines .
    Cauloside D
  • HY-N6919

    NO Synthase Inflammation/Immunology
    Cauloside C is a triterpene glycoside isolated from Caulophyllum robustum Max. Cauloside C exerts anti-inflammatory effects through the inhibition of expression of iNOS and proinflammatory cytokines .
    Cauloside C
  • HY-N1228

    Others Others
    Soyacerebroside I is a glycosphingolipid, together with Soyacerebroside II, which can be isolated from the seeds of Glycine max Merrill (Leguminosae). Soyacerebroside II shows ionophoretic activity for Ca 2+ .
    Soyacerebroside I
  • HY-12703
    KSI-3716
    1 Publications Verification

    c-Myc Autophagy Cancer
    KSI-3716 is a potent c-Myc inhibitor that blocks c-MYC/MAX binding to target gene promoters. KSI-3716 is an effective intravesical chemotherapy agent for bladder cancer .
    KSI-3716
  • HY-120115

    Olaparib-bodipy FL

    PARP Fluorescent Dye Cancer
    PARPi-FL is a small molecule and fluorescent inhibitor of PARP1. PARPi-FL is a highly selective probe and can be used as an imaging agent to detect glioblastomas in vivo. (Excitation/Emission max 507/525 nm) .
    PARPi-FL
  • HY-137551

    Protoporphyrinogen IX oxidase Others Others
    Tiafenacil is a new protoporphyrinogen IX oxidase (PPO)-inhibiting herbicide, with IC50 values of 22 to 28 nM for various plant species, including amaranth (Amaranthus tuberculatus), soybean (Glycine max), arabidopsis (Arabidopsis thaliana), and rapeseed (Brassica napus) .
    Tiafenacil
  • HY-169334

    Endogenous Metabolite Metabolic Disease
    BDK-IN-1 (compound (-)-43) is a BDK inhibitor with the IC50 of 0.23 μM and the max inhibition of 90%. BDK-IN-1 decreases the level of phospho-E1 and can be used for study of cardiometabolic diseases .
    BDK-IN-1
  • HY-133536

    PA-JF549-NHS

    Fluorescent Dye Others
    PA Janelia Fluor 549, SE (PA-JF549-NHS) is a bright photoactivatable fluorophore of JF549,SE (JF549,NHS). JF549,SE (JF549,NHS) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
    PA Janelia Fluor® 549, SE
  • HY-131021

    JF549, Azide

    Fluorescent Dye Others
    Janelia Fluor? 549, Azide (JF549, Azide) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor? products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Janelia Fluor® 549, Azide
  • HY-115796

    Others Others
    VU0477886 is a metabotropic glutamate receptor subtype 4 (mGlu4) positive allosteric modulator with potent activating activity on mGlu4 (EC50 = 95nM, 89% Glu Max), good pharmacokinetic characteristics (brain: plasma Kp = 1.3), and significant therapeutic efficacy in Parkinson's disease models.
    VU0477886
  • HY-144878
    VPC-70619
    2 Publications Verification

    c-Myc Cancer
    VPC-70619 is a potent, orally active N-Myc inhibitor. VPC-70619 blocks the N-Myc-Max heterocomplex from binding to DNA E-boxes and demonstrated strong inhibition activity against N-Myc-dependent cell lines as well as high bioavailability in both oral and intraperitoneal administration .
    VPC-70619
  • HY-135969
    Glycol chitosan
    3 Publications Verification

    Bacterial Infection
    Glycol chitosan is a chitosan derivative with ethylene glycol branches. Glycol chitosan enhances membrane permeability and leadkage in Glycine max Harosoy 63W cells. Glycol chitosan is biocompatible and biodegradable . Glycol chitosan inhibits E. coli, S. aureus and S. enteritidis growths with MIC values of 4 μg/mL, 32 μg/mL and <0.5 μg/mL, respectively .
    Glycol chitosan
  • HY-124675
    MYCMI-6
    1 Publications Verification

    NSC354961

    c-Myc Apoptosis Cancer
    MYCMI-6 (NSC354961) is a potent and selective endogenous MYC:MAX protein interactions inhibitor. MYCMI-6 blocks MYC-driven transcription and binds selectively to the MYC bHLHZip domain with a Kd of 1.6 μM. MYCMI-6 inhibits tumor cell growth in a MYC-dependent manner (IC50<0.5 μM). MYCMI-6 is not cytotoxic to normal human cells. MYCMI-6 induces apoptosis .
    MYCMI-6
  • HY-N5072
    Desmethylglycitein
    1 Publications Verification

    4',6,7-Trihydroxyisoflavone

    CDK PI3K PKC Cancer
    Desmethylglycitein (4',6,7-Trihydroxyisoflavone), a metabolite of daidzein, sourced from Glycine max with antioxidant, and anti-cancer activities. Desmethylglycitein binds directly to CDK1 and CDK2 in vivo, resulting in the suppresses CDK1 and CDK2 activity . Desmethylglycitein is a direct inhibitor of protein kinase C (PKC)α, against solar UV (sUV)-induced matrix matrix metalloproteinase 1 (MMP1) . Desmethylglycitein binds to PI3K in an ATP competitive manner in the cytosol, where it inhibits the activity of PI3K and downstream signaling cascades, leading to the suppression of adipogenesis in 3T3-L1 preadipocytes .
    Desmethylglycitein

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