2. Cell Cycle/DNA Damage Epigenetics Others
  3. PARP Fluorescent Dye
  4. PARPi-FL

PARPi-FL  (Synonyms: Olaparib-bodipy FL)

Cat. No.: HY-120115 Purity: 99.74%
COA Handling Instructions

Molarity Calculator

PARPi-FL is a small molecule and fluorescent inhibitor of PARP1. PARPi-FL is a highly selective probe and can be used as an imaging agent to detect glioblastomas in vivo. (Excitation/Emission max 507/525 nm).

For research use only. We do not sell to patients.

PARPi-FL Chemical Structure

PARPi-FL Chemical Structure

CAS No. : 1380359-84-1

Size Price Stock Quantity
1 mg USD 260 In-stock
5 mg USD 650 In-stock
10 mg USD 980 In-stock
25 mg USD 1800 In-stock
50 mg USD 2700 In-stock
100 mg USD 3950 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

PARPi-FL Related Antibodies

Top Publications Citing Use of Products

View All PARP Isoform Specific Products:

View All Isoforms
PARP PARP1 PARP2 PARP3 PARP4 TNKS1/PARP5A TNKS2/PARP5B PARP7 PARP10 PARP14 PARP15 PARP12 PARP16

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

PARPi-FL is a small molecule and fluorescent inhibitor of PARP1. PARPi-FL is a highly selective probe and can be used as an imaging agent to detect glioblastomas in vivo. (Excitation/Emission max 507/525 nm)[1][3].

Molecular Weight

640.46

Formula

C34H32BF3N6O3
CAS No.
Appearance

Solid

Color

Yellow to orange

SMILES

O=C1NN=C(CC2=CC=C(C(C(N3CCN(CC3)C(CCC4=CC=C5C=C6C(C)=CC(C)=[N]6[B+3]([F-])([N-]54)[F-])=O)=O)=C2)F)C7=C1C=CC=C7
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (78.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5614 mL 7.8069 mL 15.6138 mL
5 mM 0.3123 mL 1.5614 mL 3.1228 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5614 mL 7.8069 mL 15.6138 mL 39.0344 mL
5 mM 0.3123 mL 1.5614 mL 3.1228 mL 7.8069 mL
10 mM 0.1561 mL 0.7807 mL 1.5614 mL 3.9034 mL
15 mM 0.1041 mL 0.5205 mL 1.0409 mL 2.6023 mL
20 mM 0.0781 mL 0.3903 mL 0.7807 mL 1.9517 mL
25 mM 0.0625 mL 0.3123 mL 0.6246 mL 1.5614 mL
30 mM 0.0520 mL 0.2602 mL 0.5205 mL 1.3011 mL
40 mM 0.0390 mL 0.1952 mL 0.3903 mL 0.9759 mL
50 mM 0.0312 mL 0.1561 mL 0.3123 mL 0.7807 mL
60 mM 0.0260 mL 0.1301 mL 0.2602 mL 0.6506 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

PARPi-FL Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PARPi-FL1380359-84-1Olaparib-bodipy FLPARPFluorescent Dyepoly ADP ribose polymerasePARP1 InhibitorRadiationChemotherapyGlioblastomasInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
PARPi-FL
Cat. No.:
HY-120115
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.