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MC-SN38

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-136170
    MC-SN38
    1 Publications Verification

    		 Drug-Linker Conjugates for ADC Cancer
    MC-SN38 is a agent-linker conjugate composed of a potent microtubule-disrupting agent SN38 and a non-cleavable MC linker to make antibody agent conjugate (ADC). SN-38, an active metabolite of the Topoisomerase I inhibitor Irinotecan, inhibits DNA synthesis and causes frequent DNA single-strand breaks .
    MC-SN38

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