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Results for "

MTH1 Degrader

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-161162
    aTAG 2139

    CFT-2139

    		 DNA/RNA Synthesis Others
    aTAG 2139 (CFT-2139) is an aTAG-based MTH1 fusion protein degrader with a DC50 value of 1.1 nM. aTAG 2139 has a Ki value of 2.1 nM for MTH1 .
    aTAG 2139
  • HY-163168
    aTAG 4531

    CFT-4531

    		 DNA/RNA Synthesis Cancer
    aTAG 4531 (CFT-4531) is a potent, selective, and onmechanism tool degrader of MTH1 with DC50 value of 0.28 nM and Ki value of 1.8 nM. degradation activity is due to the intricate formation of the ternary complex between the MTH1 aTAG, CRBN E3 ligase, and aTAG tool degrader .
    aTAG 4531
  • HY-161161
    aTAG 2139-NEG

    		Others Others
    aTAG 2139-NEG (Compound 23) binds to MTH1 and has no degradative activity with a Ki value of 2.0 nM. aTAG 2139-NEG serves as aTAG 2139 negative control .
    aTAG 2139-NEG

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