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N-Acetyl-4-benzoquinone Imine

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W017464
    NAPQI

    N-Acetyl-4-benzoquinone Imine

    		 Drug Metabolite Endogenous Metabolite Metabolic Disease
    NAPQI is the toxic metabolite of Acetaminophen (HY-66005). NAPQI is also an inhibitor of enzymes in the vitamin K cycle. NAPQI is rapidly detoxified by glutathione (GSH), but in situations of GSH deficiency, excess NAPQI reacts with cysteine residues in proteins, causing cell death and toxicity in the liver .
    NAPQI

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