Search Result

Results for "

NBI-56418-<sup>13</sup>C,d<sub>3</sub>

" in MedChemExpress (MCE) Product Catalog:

By Targets:	P-glycoprotein (5) 5 alpha Reductase (1) 5-HT Receptor (6) Acyltransferase (1) ADC Antibody (15) ADC Cytotoxin (13) ADC Linker (1) Adenosine Receptor (1) Adrenergic Receptor (3) AIM2 (1) Akt (4) ALCAM/CD166 (1) Aldehyde Dehydrogenase (ALDH) (1) Amino Acid Derivatives (3) Aminopeptidase (7) AMPK (1) Amyloid-β (4) Anaplastic lymphoma kinase (ALK) (2) Androgen Receptor (4) Antibiotic (44) Antibody-Drug Conjugates (ADCs) (13) Apelin Receptor (APJ) (6) Apical Sodium-Dependent Bile Acid Transporter (1) Apoptosis (102) Arenavirus (1) Aryl Hydrocarbon Receptor (6) Aurora Kinase (3) Autophagy (60) Bacterial (77) Bcl-2 Family (1) Bcr-Abl (2) Beta-lactamase (1) Beta-secretase (1) Biochemical Assay Reagents (18) Btk (3) c-Fms (2) c-Kit (3) c-Met/HGFR (1) c-Myc (1) C-type Lectin-like Receptor (CTLR) (1) Cadherin (1) Calcium Channel (16) Carbonic Anhydrase (3) Caspase (5) Cathepsin (1) CCR (1) CD19 (20) CD2 (2) CD20 (18) CD22 (11) CD276/B7-H3 (3) CD28 (19) CD3 (50) CD38 (21) CD47 (33) CD6 (1) CD73 (40) CD74 (2) CDK (1) CGRP Receptor (1) Checkpoint Kinase (Chk) (1) Cholinesterase (ChE) (1) Complement System (11) COX (8) CRAC Channel (1) CTLA-4 (1) CXCR (10) Cyclophilin (2) Cytochrome P450 (5) Dengue virus (1) Dipeptidyl Peptidase (1) Disulfidptosis (1) DNA Methyltransferase (1) DNA/RNA Synthesis (55) Dopamine Receptor (6) Drug Derivative (1) Drug Intermediate (1) Drug Metabolite (5) Drug-Linker Conjugates for ADC (6) Dynamin (1) DYRK (1) E1/E2/E3 Enzyme (3) E3 Ligase Ligand-Linker Conjugates (1) EAAT (1) EBV (1) EGFR (9) Endogenous Metabolite (411) Epigenetic Reader Domain (5) ERK (7) Estrogen Receptor/ERR (8) FAK (1) Fatty Acid Synthase (FASN) (2) Ferroptosis (16) FGFR (1) Flavivirus (2) FLT3 (1) Fluorescent Dye (10) Fungal (8) FXR (2) G protein-coupled Bile Acid Receptor 1 (2) GABA Receptor (9) Galectin (1) Gap Junction Protein (1) Glucocorticoid Receptor (6) Glutaminase (1) Glutathione Reductase (1) GlyT (1) GnRH Receptor (2) GSK-3 (1) HBV (2) HCV (2) HDAC (6) Hexokinase (3) HIF/HIF Prolyl-Hydroxylase (6) Histamine Receptor (1) Histone Acetyltransferase (2) Histone Demethylase (4) Histone Methyltransferase (5) HIV (44) HIV Protease (3) HPV (2) HSP (2) HSV (10) Huntingtin (1) IFNAR (10) IGF-1R (2) iGluR (10) IKK (3) Imidazoline Receptor (1) Influenza Virus (14) Insulin Receptor (1) Integrin (12) Interleukin Related (35) IRAK (2) Isotope-Labeled Compounds (495) Itk (2) JAK (2) JNK (1) Keap1-Nrf2 (2) Ketohexokinase (2) Kinesin (1) Lactate Dehydrogenase (2) LAG-3 (2) Leukotriene Receptor (1) Ligands for E3 Ligase (3) Liposome (8) Lipoxygenase (2) LPL Receptor (2) mAChR (1) MAP4K (2) MAPKAPK2 (MK2) (1) MDM-2/p53 (1) Melanocortin Receptor (1) mGluR (10) Microtubule/Tubulin (8) Mitochondrial Metabolism (3) Mitophagy (12) MMP (2) MNK (1) Molecular Glues (6) Monoamine Oxidase (1) mTOR (2) Na+/K+ ATPase (2) nAChR (1) NADPH Oxidase (1) Necroptosis (1) Neprilysin (2) Neurokinin Receptor (1) NF-κB (13) NO Synthase (11) NOD-like Receptor (NLR) (3) Notch (2) NTPDase (4) Nuclear Factor of activated T Cells (NFAT) (2) Nuclear Hormone Receptor 4A/NR4A (1) Nucleoside Antimetabolite/Analog (43) Opioid Receptor (4) Orexin Receptor (OX Receptor) (2) Organoid (1) Orthopoxvirus (8) Oxidative Phosphorylation (1) P-selectin (1) P2X Receptor (2) P2Y Receptor (4) p38 MAPK (2) PAI-1 (1) PAK (2) Parasite (18) PARP (1) PD-1/PD-L1 (27) PGE synthase (1) Phosphatase (9) Phosphodiesterase (PDE) (2) Phospholipase (5) PI3K (5) PKA (1) PKC (2) PKD (1) Polo-like Kinase (PLK) (1) Potassium Channel (6) PPAR (3) Progesterone Receptor (4) Prostaglandin Receptor (3) PROTAC Linkers (2) PROTACs (3) Proteasome (1) Pyroptosis (2) RAD51 (2) Radionuclide-Drug Conjugates (RDCs) (4) RAR/RXR (13) Reactive Oxygen Species (28) ROCK (1) ROR (4) ROS Kinase (1) RSV (3) SARS-CoV (12) Scavenger Receptor Class B type I (SR-BI） (2) Ser/Thr Protease (2) SGLT (1) SHP2 (2) Sirtuin (4) Small Interfering RNA (siRNA) (102) Sodium Channel (8) Src (2) STAT (5) STING (6) Target Protein Ligand-Linker Conjugates (1) TGF-beta/Smad (2) TGF-β Receptor (4) Thrombin (2) Thrombopoietin Receptor (2) Thymidylate Synthase (5) Thyroid Hormone Receptor (3) Tie (1) Tim3 (1) TNF Receptor (61) Toll-like Receptor (TLR) (7) Topoisomerase (3) Transferrin Receptor (2) Transmembrane Glycoprotein (14) Trk Receptor (3) TRP Channel (2) Tyrosinase (3) VD/VDR (2) VEGFR (9) Virus Protease (2) Wee1 (1) Wnt (1) Xanthine Oxidase (2) α-synuclein (1) β-catenin (1)
By Research Areas:	Cancer (635) Cardiovascular Disease (56) Endocrinology (25) Infection (163) Inflammation/Immunology (453) Metabolic Disease (218) Neurological Disease (121)
Click Chemistry:	Labeling and Fluorescence Imaging (2) Azide (2) Tetrazine (1) Alkynes (6)
Oligonucleotides:	Aptamers (2) Pre-designed siRNA Sets (101) CpG ODNs (8) mRNA (3) Solubilizing Agents (1) Cationic Lipids (1) Phospholipids (1) Antisense Oligonucleotides (2) siRNAs (101)

1624

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

495

Inhibitory Antibodies

Natural
Products

2335

Recombinant Proteins

700

Isotope-Labeled Compounds

292

Antibodies

Click Chemistry

119

Oligonucleotides

Targets Recommended: P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0898S

Catechin-13C3 (+)-Catechin-<sup>13sup>C<sub>3sub>; Cianidanol-<sup>13sup>C<sub>3sub>; Catechuic acid-<sup>13sup>C<sub>3sub>	COX Apoptosis Influenza Virus Endogenous Metabolite	Cancer
Catechin- ¹³C₃ is the ¹³C-labeled Catechin. Catechin ((+)-Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.

HY-14369

Elagolix sodium NBI-56418 sodium	GnRH Receptor Nuclear Factor of activated T Cells (NFAT)	Endocrinology Cancer
Elagolix sodium is a highly effective, selective, oral-active, short-term, non-peptide gonadotropin-releasing hormone receptor (GnRH receptor) antagonist (K_D = 54 pM) and NFAT inhibitor, which can be used to study pain related to endometriosis. ^[3] .

HY-40354S

Tofacitinib-13C3 Tasocitinib-<sup>13sup>C<sub>3sub>; CP-690550-<sup>13sup>C<sub>3sub>	JAK Apoptosis	Inflammation/Immunology Cancer
Tofacitinib- ¹³C₃ is the ¹³C-labeled Tofacitinib. Tofacitinib is an orally available JAK3/2/1 inhibitor with IC50s of 1, 20, and 112 nM, respectively.

HY-A0253S

Cefacetrile-13C3 Cephacetrile-<sup>13sup>C<sub>3sub>; Cephacetril-<sup>13sup>C<sub>3sub>	Antibiotic Bacterial Isotope-Labeled Compounds	Others
Cefacetrile- ¹³C₃ is the ¹³C₃ labeled Cefacetrile.

HY-B0234S

Estrone-13C3 E1-<sup>13sup>C<sub>3sub>; Oestrone-<sup>13sup>C<sub>3sub>	Estrogen Receptor/ERR Endogenous Metabolite	Endocrinology Cancer
Estrone- ¹³C₃ is the ¹³C-labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].

HY-B1331S1

Cyromazine-13C3 Cyromazin-<sup>13sup>C<sub>3sub>; CGA-72662-<sup>13sup>C<sub>3sub>	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
Cyromazine- ¹³C₃ is the ¹³C₃ labeled Cyromazine. Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects.

HY-100196S1

Pyrroloquinoline quinone-13C3 sodium PQQ-<sup>13sup>C<sub>3sub> sodium; Methoxatin-<sup>13sup>C<sub>3sub> sodium	Endogenous Metabolite	Inflammation/Immunology
Pyrroloquinoline quinone-13C3 (sodium) is an isotope of Pyrroloquinoline quinone. Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function .

HY-B1804S

Tricaprilin-13C3 Trioctanoin-<sup>13sup>C<sub>3sub>; Glyceryl trioctanoate-<sup>13sup>C<sub>3sub>	Isotope-Labeled Compounds Endogenous Metabolite	Neurological Disease
Tricaprilin-13C3 is a deuterated labeled Tricaprilin . Tricaprilin (Trioctanoin) is used in study for patients with mild to moderate Alzheimer's disease and has a role as an anticonvulsant and a plant metabolite ^[3].

HY-W653853

Ritonavir-13C3 ABT 538-<sup>13sup>C<sub>3sub>; RTV-<sup>13sup>C<sub>3sub>	Isotope-Labeled Compounds Apoptosis SARS-CoV HIV Protease HIV	Cancer
Ritonavir- ¹³C₃ is ¹³C labeled Ritonavir. Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CL ^pro inhibitor with an IC₅₀ of 1.61 μM .

HY-B0389S18

D-Glucose-13C3-1 Glucose-<sup>13sup>C<sub>3sub>-1; D-(+)-Glucose-<sup>13sup>C<sub>3sub>-1; Dextrose-<sup>13sup>C<sub>3sub>-1	Endogenous Metabolite	Metabolic Disease
D-Glucose- ¹³C₃-1 is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-B0389S9

D-Glucose-13C3-2 Glucose-<sup>13sup>C<sub>3sub>-2; D-(+)-Glucose-<sup>13sup>C<sub>3sub>-2; Dextrose-<sup>13sup>C<sub>3sub>-2	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
D-Glucose- ¹³C₃-2 is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-W654126

Cytarabine-13C3 Cytosine β-D-arabinofuranoside--<sup>13sup>C<sub>3sub>; Cytosine Arabinoside--<sup>13sup>C<sub>3sub>; Ara-C-<sup>13sup>C<sub>3sub>	Isotope-Labeled Compounds	Others
Cytarabine- ¹³C₃ (Cytosine β-D-arabinofuranoside- ¹³C₃) is ¹³C labeled Cytarabine .

HY-100532S

CD437-13C6 AHPN-<sup>13sup>C<sub>6sub>	Isotope-Labeled Compounds RAR/RXR Autophagy	Cancer
CD437- ¹³C₆ is the ¹³C- and deuterium labeled CD437. CD437 is a selective Retinoic Acid Receptor γ (RARγ) agonist.

HY-N0650S

L-Serine-13C3 (-)-Serine-<sup>13sup>C<sub>3sub>; (S)-Serine-<sup>13sup>C<sub>3sub>	Endogenous Metabolite	Cancer
L-Serine- ¹³C₃ is the ¹³C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-B0495S4

Lamotrigine-13C3 LTG-<sup>13sup>C<sub>3sub>; BW430C-<sup>13sup>C<sub>3sub>	Sodium Channel Autophagy	Neurological Disease
Lamotrigine- ¹³C₃ is the ¹³C-labeled Lamotrigine. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al[1][2].

HY-N0680S3

Thiamine-13C3 hydrochloride Thiamine chloride-<sup>13sup>C<sub>3sub> hydrochloride; Vitamin B1-<sup>13sup>C<sub>3sub> hydrochloride	Isotope-Labeled Compounds Endogenous Metabolite Apoptosis HBV	Neurological Disease
Thiamine- ¹³C₃ (hydrochloride) is the ¹³C-labeled Thiamine (hydrochloride). Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.

HY-14605S

Rasagiline-13C3 mesylate (R)-AGN1135-<sup>13sup>C<sub>3sub> mesylate; TVP1012-<sup>13sup>C<sub>3sub> mesylate	Isotope-Labeled Compounds	Others
Rasagiline- ¹³C₃ ((R)-AGN1135- ¹³C₃; TVP1012- ¹³C₃) mesylateis the deuterium labeledRasagiline (mesylate)(HY-14605) . Rasagiline (R-AGN1135) mesylate is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC₅₀s of 4.43?nM and 412?nM for rat brain MAO B and A activity, respectively .

HY-14789

(R)-Elagolix NBI-56418	GnRH Receptor Nuclear Factor of activated T Cells (NFAT)	Endocrinology Cancer
Elagolix is a highly effective, selective, oral-active, short-term, non-peptide gonadotropin-releasing hormone receptor (GnRH receptor) antagonist (K_D = 54 pM) and NFAT inhibitor, which can be used to study pain related to endometriosis. ^[3] .

HY-Y0921S3

(±)-1,2-Propanediol-13C3 1,2-(RS)-Propanediol-<sup>13sup>C<sub>3sub>; 1,2-Propylene glycol-<sup>13sup>C<sub>3sub>; Propylene glycol-<sup>13sup>C<sub>3sub>	Endogenous Metabolite Isotope-Labeled Compounds	Neurological Disease
(±)-1,2-Propanediol- ¹³C₃ is ¹³C labeled (±)-1,2-Propanediol (HY-Y0921). (±)-1, 2-propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol that is often used as an excipient in many active molecular preparations to increase the solubility and stability of the active molecule. (±)-1, 2-propanediol can affect the neurobehavior of zebrafish .

HY-14605BS

Rasagiline-13C3 mesylate racemic AGN1135-<sup>13sup>C<sub>3sub>; TVP1012-<sup>13sup>C<sub>3sub> racemic	Isotope-Labeled Compounds Monoamine Oxidase	Neurological Disease
Rasagiline- ¹³C₃ (mesylate racemic) is a ¹³C-labeled Rasagiline mesylate racemic. Rasagiline mesylate racemic is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor[1]. Rasagiline-13C3 (mesylate racemic) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0891S1

17α-Hydroxyprogesterone-13C3 17-Hydroxyprogesterone-<sup>13sup>C<sub>3sub>; 17-OHP-<sup>13sup>C<sub>3sub>	Progesterone Receptor Endogenous Metabolite	Others
17α-Hydroxyprogesterone- ¹³C₃ is the ¹³C-labeled 17α-Hydroxyprogesterone. 17α-Hydroxyprogesterone (17-Hydroxyprogesterone) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.

HY-N0086S3

N6-Methyladenosine-13C3 6-Methyladenosine-<sup>13sup>C<sub>3sub>; N-Methyladenosine-<sup>13sup>C<sub>3sub>	Isotope-Labeled Compounds Influenza Virus Endogenous Metabolite	Infection
N6-Methyladenosine- ¹³C₃ (6-Methyladenosine- ¹³C₃) is ¹³C-labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities ^[3].

HY-W777148

Anagrelide-13C3 BL 4162A-<sup>13sup>C<sub>3sub>; BMY 26538-01-<sup>13sup>C<sub>3sub>	Isotope-Labeled Compounds	Others
Anagrelide- ¹³C₃ (BL 4162A- ¹³C₃) is ¹³C labeled Anagrelide .

HY-D0184S3

2'-Deoxycytidine-13C9,15N3 Deoxycytidine-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>3sub>; Cytosine deoxyriboside-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>3sub>; Deoxyribose cytidine-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>3sub>	Isotope-Labeled Compounds Endogenous Metabolite	Others
2'-Deoxycytidine- ¹³C₉, ¹⁵N₃ (Deoxycytidine- ¹³C₉, ¹⁵N₃; Cytosine deoxyriboside- ¹³C₉, ¹⁵N₃; Deoxyribose cytidine- ¹³C₉, ¹⁵N₃) is ¹³C and ¹⁵N-labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).

HY-113008AS

cis-Urocanic acid-13C3 (Z)-Urocanic acid-<sup>13sup>C<sub>3sub>; cis-UCA-<sup>13sup>C<sub>3sub>	Isotope-Labeled Compounds 5-HT Receptor	Inflammation/Immunology
cis-Urocanic acid- ¹³C₃ is the ¹³C-labeled cis-Urocanic acid. cis-Urocanic acid is a 5-HT2A receptor agonist. cis-Urocanic acid binds to 5-HT receptor with relatively high affinity (Kd=4.6 nM). cis-Urocanic acid is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor[1].

HY-B1342S3

Vitamin A-13C3 Vitamin A1-<sup>13sup>C<sub>3sub>; all-trans-Retinol-<sup>13sup>C<sub>3sub>	Isotope-Labeled Compounds	Others
Vitamin A- ¹³C₃ (Vitamin A1- ¹³C₃; all-trans-Retinol- ¹³C₃) is a ¹³C-labeled Vitamin A/Vitamin A (HY-B1342). Vitamin A is an endogenous metabolite.

HY-N0610AS2

Cinnamic acid-13C3 3-Phenylacrylic acid-<sup>13sup>C<sub>3sub>; β-Phenylacrylic acid-<sup>13sup>C<sub>3sub>	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
Cinnamic acid- ¹³C₃ (3-Phenylacrylic acid- ¹³C₃) is the ¹³C labeled Cinnamic acid (HY-N0610A). Cinnamic acid has potential use in cancer intervention, with IC₅₀s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells .

HY-18569S4

3-Indoleacetic acid-13C6 Indole-3-acetic acid-<sup>13sup>C<sub>6sub>; 3-IAA-<sup>13sup>C<sub>6sub>	Endogenous Metabolite Molecular Glues	Others
3-Indoleacetic acid- ¹³C₆ is the ¹³C labeled 3-Indoleacetic acid[1]. 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division .

HY-W768345

D-(+)-Trehalose-13C12 D-Trehalose-<sup>13sup>C<sub>12sub>; α,α-Trehalose-<sup>13sup>C<sub>12sub>	Endogenous Metabolite Isotope-Labeled Compounds	Others
D-(+)-Trehalose-13C12 is a ¹³C isotope labeled version of D-(+)-Trehalose (HY-N1132). D-(+)-Trehalose,which is widespread, can be used as a food ingredient and pharmaceutical excipient .

HY-110382S

13C20,15N10-Cyclic di-GMP sodium <sup>13sup>C<sub>20sub>,<sup>15sup>N<sub>10sub>-c-di-GMP, <sup>13sup>C<sub>20sub>,<sup>15sup>N<sub>10sub>-Cyclic diguaylate, <sup>13sup>C<sub>20sub>,<sup>15sup>N<sub>10sub>-3’,5’-Cyclic diguaylic Acid	Isotope-Labeled Compounds Endogenous Metabolite STING	Cancer
¹³C20, ¹⁵N10-Cyclic di-GMP ( ¹³C20, ¹⁵N10-c-di-GMP) is ¹³C and ¹⁵N labeled Cyclic-di-GMP (disodium). Cyclic-di-GMP disodium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP disodium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP disodium can be used in cancer research ^[3] .

HY-Y0721S

3-Bromofluorobenzene-13C6 m-Bromofluorobenzene-<sup>13sup>C<sub>6sub>; m-Fluorobromobenzene-<sup>13sup>C<sub>6sub>; m-Fluorophenyl bromide-<sup>13sup>C<sub>6sub>	Isotope-Labeled Compounds	Others
3-Bromofluorobenzene- ¹³C₆ is the ¹³C labeled 3-Bromofluorobenzene[1].

HY-N0304S1

L-DOPA-13C6 Levodopa-<sup>13sup>C<sub>6sub>; 3,4-Dihydroxyphenylalanine-<sup>13sup>C<sub>6sub>	Dopamine Receptor Endogenous Metabolite	Neurological Disease
L-DOPA- ¹³C₆ is the ¹³C-labled L-DOPA . L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease ^[3] .

HY-Y0219S

1,2,4-Triazole-13C2,15N3 s-Triazole<sup>13sup>C<sub>2sub>,<sup>15sup>N<sub>3sub>; Pyrrodiazole<sup>13sup>C<sub>2sub>,<sup>15sup>N<sub>3sub>	Isotope-Labeled Compounds	Others
NSC 83128- ¹³C₂, ¹⁵N₃ is the ¹³C and ¹⁵N labeled NSC 83128[1].

HY-B0150S1

Nicotinamide-15N,13C3 Niacinamide-<sup>15sup>N,<sup>13sup>C<sub>3sub>; Nicotinic acid amide-<sup>15sup>N,<sup>13sup>C<sub>3sub>	Endogenous Metabolite Sirtuin	Neurological Disease Cancer
Nicotinamide- ¹⁵N, ¹³C₃ is the ¹³C-labeled and ¹⁵N-labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1.

HY-B0412S3

Estriol-13C3 Oestriol-<sup>13sup>C<sub>3sub>	Estrogen Receptor/ERR Endogenous Metabolite	Cancer
Estriol- ¹³C₃ is the ¹³C-labeled Estriol. Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells.

HY-B1659S5

Glycerol-13C3 Glycerin-<sup>13sup>C<sub>3sub>	Endogenous Metabolite	Cancer
Glycerol- ¹³C₃ is the ¹³C labeled Glycerol[1]. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis[2][3][4].

HY-N0136S1

(±)-Taxifolin-13C3 (±)-Dihydroquercetin-<sup>13sup>C<sub>3sub>	Autophagy Tyrosinase	Inflammation/Immunology
(±)-Taxifolin-13C3 ((±)-Dihydroquercetin-13C3) is a derivative of (±)-Taxifolin, labeled with 13C3. (±)-Taxifolin is the racemate of Taxifolin. Taxifolin exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC₅₀ value of 193.3 μM . Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity .

HY-B0111RS

Drospirenone-13C3 Dihydrospirorenone-<sup>13sup>C<sub>3sub>	Isotope-Labeled Compounds	Endocrinology
Drospirenone- ¹³C₃ is ¹³C labeled Drospirenone. Drospirenone (Dihydrospirorenone) is a synthetic progesterone that is an analog of Spironolactone .

HY-Y0589S

m-Cyanobenzoic acid-13C6 3-Carboxybenzonitrile-<sup>13sup>C<sub>6sub>; 3-Cyanobenzoic acid-<sup>13sup>C<sub>6sub>; m-Carboxybenzonitrile-<sup>13sup>C<sub>6sub>	Isotope-Labeled Compounds	Others
m-Cyanobenzoic acid- ¹³C₆ is the ¹³C labeled m-Cyanobenzoic acid[1].

HY-B0178AS

Guanidine-13C,15N3 hydrochloride Guanidinium-<sup>13sup>C,<sup>15sup>N<sub>3sub> (chloride); Aminoformamidine-<sup>13sup>C,<sup>15sup>N<sub>3sub> (hydrochloride)	Endogenous Metabolite	Metabolic Disease
Guanidine- ¹³C, ¹⁵N₃ (hydrochloride)is the ¹³C-labeled and ¹⁵N-labeled Guanidine hydrochloride. Guanidine hydrochloride (Guanidinium chloride) a strong chaotrope, is also a strong denaturant of proteins[1][2].

HY-N0650S5

L-Serine-13C3,15N (-)-Serine-<sup>13sup>C<sub>3sub>,<sup>15sup>N; (S)-Serine-<sup>13sup>C<sub>3sub>,<sup>15sup>N	Endogenous Metabolite	Cancer
L-Serine- ¹³C₃, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-W015913S

Sodium 2-oxopropanoate-13C3 Sodium pyruvate-<sup>13sup>C<sub>3sub>	Reactive Oxygen Species Endogenous Metabolite	Metabolic Disease
Sodium 2-oxopropanoate- ¹³C₃ is the ¹³C-labeled Sodium 2-oxopropanoate. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS[1][2].

HY-139145S

Etbicyphat-13C3 Trimethylopropane phosphate-<sup>13sup>C<sub>3sub>	GABA Receptor	Neurological Disease
Etbicyphat- ¹³C₃ is the ¹³C labeled Etbicyphat (HY-139145). Etbicyphat is a potent GABA(A) receptors competitive antagonist. Etbicyphat induces epileptiform activities in hippocampal CA1 neurons, and binds to the GABA(A)-benzodiazepine receptors[1][2].

HY-12542S

Dantrolene-13C3 F 368-<sup>13sup>C<sub>3sub>	Isotope-Labeled Compounds Glutathione Reductase	Neurological Disease Inflammation/Immunology
Dantrolene- ¹³C₃ is the ¹³C₃ labeled Dantrolene. Dantrolene (F368), a muscle relaxant, non-competitively inhibits human erythrocyte glutathione reductase. Ki and IC50 values are 111.6 μM and 52.3 μM, respectively. Dantrolene is a ryanodine receptor antagonist and Ca2+ signaling stabilizer. Dantrolene can be used for the research of muscle spasticity, malignant hyperthermia, Huntington's disease and other neuroleptic malignant syndrome.

HY-W769714

Favipiravir-13C3 T-705-<sup>13sup>C<sub>3sub>	Isotope-Labeled Compounds Antibiotic Bacterial	Infection
Favipiravir- ¹³C3 is the ¹³C labeled isotope of Favipiravir- ¹³C3(HY-14768 ).Favipiravir (T-705) is a potent viral RNA polymerase inhibitor, it is phosphoribosylated by cellular enzymes to its active form, Favipiravir-ribofuranosyl-5′-triphosphate (RTP). Favipiravir-RTP inhibits the influenza viral RNA-dependent RNA polymerase (RdRP) activity with an IC₅₀ of 341 nM.

HY-127035S1

Tristearin-13C3 Glycerol tristearate-<sup>13sup>C<sub>3sub>	Isotope-Labeled Compounds Endogenous Metabolite	Others
Tristearin- ¹³C₃ (Glycerol tristearate- ¹³C₃) is ¹³C labeled Tristearin. Tristearin is a triglyceride derived from three units of stearic acid .

HY-15306S

Eltrombopag-13C4 1 Publications Verification SB-497115-<sup>13sup>C<sub>4sub>	Thrombopoietin Receptor Bacterial Apoptosis	Infection Cardiovascular Disease Cancer
Eltrombopag- ¹³C₄ (SB-497115- ¹³C₄) is ^{13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells ^[3] .}

HY-B0158S5

Cytidine-13C9,15N3 Cytosine β-D-riboside-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>3sub>; Cytosine-1-β-D-ribofuranoside-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>3sub>	Nucleoside Antimetabolite/Analog Endogenous Metabolite	Neurological Disease
Cytidine- ¹³C₉, ¹⁵N₃ is the ¹³C and ¹⁵N labeled Cytidine[1]. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function[2][3][4].

HY-W009162S5

Cytidine 5′-monophosphate-13C9,15N3 dilithium 5'-Cytidylic acid-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>3sub> dilithium; 5'-CMP-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>3sub> dilithium	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
Cytidine 5′-monophosphate- ¹³C₉, ¹⁵N₃ (5'-Cytidylic acid- ¹³C₉, ¹⁵N₃ dilithium; 5'-CMP- ¹³C₉, ¹⁵N₃) dilithium is ¹³C and ¹⁵N-labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.

HY-101400S2

Deoxycytidine triphosphate-13C9,15N3 dilithium dCTP-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>3sub> dilithium; 2′-Deoxycytidine-5′-triphosphate-<sup>13sup>C<sub>9sub>,<sup>15sup>N<sub>3sub> dilithium	Isotope-Labeled Compounds Nucleoside Antimetabolite/Analog DNA/RNA Synthesis Endogenous Metabolite	Metabolic Disease
Deoxycytidine triphosphate- ¹³C₉, ¹⁵N₃ (dCTP- ¹³C₉, ¹⁵N₃ dilithium; 2′-Deoxycytidine-5′-triphosphate- ¹³C₉, ¹⁵N₃) dilithium is ¹³C and ¹⁵N-labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-125833

Alpha-Naphthoflavone 5+ Cited Publications	Flavonoids Flavones Source classification Indigofera heterantha Wall. ex Brand. Plants Compositae Disease Research Fields Cancer	Cytochrome P450 Aryl Hydrocarbon Receptor Apoptosis
Alpha-Naphthoflavone is an orally active flavonoid that is a potent, competitive inhibitor of aromatase< b>aromatase. < b > IC < sub > 50 < / sub > < / b > and < b > K < sub > I < / sub > < / b > value were 0.5 and 0.2 microns. Alpha-Naphthoflavone can inhibit cell proliferation and induce apoptosis ^[3] .

HY-W011474

Geranylgeraniol	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[3] .

HY-P2274

Argifin	Infection Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Disease Research Fields	Parasite
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC₅₀s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively .

HY-W011474R

Geranylgeraniol (Standard)	Structural Classification Natural Products Microorganisms	NF-κB
Geranylgeraniol (Standard) is the analytical standard of Geranylgeraniol. This product is intended for research and analytical applications. Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model ^[3][4].

HY-N0662

Amentoflavone 5+ Cited Publications Didemethyl-ginkgetin	Structural Classification Flavonoids Classification of Application Fields Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring Disease Research Fields Cancer	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase ^[3] .

HY-147089

PRRSV/CD163-IN-1	Infection Structural Classification Alkaloids Classification of Application Fields Other Alkaloids Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Bacterial Endogenous Metabolite
PRRSV/CD163-IN-1 is a *PRRSV/CD163* inhibitor. PRRSV/CD163-IN-1 can inhibit the interaction between the PRRSV glycoprotein (GP2a or GP4) and the CD163-SRCR5 domain. PRRSV/CD163-IN-1 can be used for the research of porcine reproductive and respiratory syndrome (PRRS) .

HY-N11799

Neochilenin 3-O-Methylquercetin 4′-O-glucoside	Structural Classification Flavonoids Source classification Plants Compositae Other Flavonoids	Others
Neochilenin (3-O-Methylquercetin 4 '-O-glucoside) is a glycoside of 3-O-methylquercetin, which can be isolated from the sub-family Cereoideae (Cactaceae). .

HY-N10192

Aculene D	Infection Microorganisms Classification of Application Fields Terpenoids Sesquiterpenes Source classification Disease Research Fields	Endogenous Metabolite Bacterial
Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .

HY-N12231

Carbazomycin B	Structural Classification Monophenols Microorganisms Source classification Phenols	Antibiotic Bacterial Lipoxygenase
Carbazomycin B is a bacterial metabolite and can be isolated from Streptomyces. Carbazomycin B is an antifungal and antibacterial agent. Carbazomycin B inhibits 5-lipoxygenase (5-LO) activity in extract from RBL-1 cell with the IC₅₀ Of 1.5 µM ^[1]sup>[2]sup>[3]sup>[4].

HY-N0662R

Amentoflavone (Standard)	Structural Classification Flavonoids Source classification Phenols Polyphenols Selaginellaceae Plants Biflavones Selaginella tamariscina (P. Beauv.) Spring	Reactive Oxygen Species Apoptosis Bacterial Fungal RSV GABA Receptor
Amentoflavone (Standard) is the analytical standard of Amentoflavone. This product is intended for research and analytical applications. Amentoflavone (Didemethyl-ginkgetin) is a potent and orally active GABA(A) negative modulator. Amentoflavone also shows anti-inflammatory, antioxidative, anti-viral, anti-tumor, anti-radiation, anti-fungal, antibacterial activity. Amentoflavone induces apoptosis and cell cycle arrest at sub-G1 phase ^[3] .

HY-N11122

7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol	Structural Classification Natural Products Rhodiola rosea Linn. Source classification Crassulaceae Plants	Others
7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol is a cuminol glycoside. 7-[α-L-Arabinopyranosyl-(1→6)-β-D-glucopyranosyloxy]cuminol can be isolated from Rhodiola rosea sup>[1].

HY-N8824

Maackiaflavanone	Structural Classification Flavonoids Leguminosae Flavonones Source classification Maackia amurensis Rupr. et Maxim. Plants	Others
Maackiaflavanone (compound 4) is a kind of prenylated flavanone. Maackia can be isolated from M. amurensi.

HY-N3872

Ethyl β-D-glucopyranoside	Scabiosa stellata L. Structural Classification Natural Products Caprifoliaceae Source classification Plants	Others
Ethyl β-D-glucopyranoside (compound 10) is a kind of phenolic compound. Ethyl β-D-glucopyranoside can be isolated from ethanolic extract of Scabiosa stellata LS.

HY-N8859

Isoiridogermanal 16-Hydroxyiridal	Structural Classification Natural Products Source classification Lridaceae Plants
Isoiridogermanal can be isolated from the extract of rhizomes of Iris tectorum Maxim. Isoiridogermanal is cytotoxic with IC50 values of 11 μM and 23 μM against MCF-7 and C32 cell lines.

HY-N3980

Guaiol Champacol; Guaiac alcohol	Infection Structural Classification Natural Products Classification of Application Fields Source classification Distemonanthus benthamianus Baill. Plants Compositae Disease Research Fields	Autophagy RAD51
Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC₅₀ of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions ^[3] ^{[4]sup .}

HY-N8930

Eupatorin-5-methyl ether	Structural Classification Galinsoga parviflora Cav. Flavonoids Flavones Labiatae Source classification Plants	Others
Eupatorin-5-methyl ether (TMF) can be isolated from Orthosiphon stamineus. Eupatorin-5-methyl ether is a kind of flavonoid compound. Eupatorin-5-methyl ether inhibits NO production (IC50 5.5 μM).

HY-N3980R

Guaiol (Standard)	Structural Classification Natural Products Source classification Distemonanthus benthamianus Baill. Plants Compositae	Autophagy RAD51
Guaiol (Standard) is the analytical standard of Guaiol. This product is intended for research and analytical applications. Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC50 of 0.01 µg/mL. Guaiol can be used in research related to cancer, infections, cardiovascular diseases, and inflammatory conditions ^[3][4] .

HY-111054A

N-methyl-N-dithiocarboxyglucamine sodium MDCG sodium	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
N-methyl-N-dithiocarboxyglucamine (MDCG) sodium mobilizes and promotes excretion of metallothionein-bound ¹⁰⁹Cd in mouse model. N-methyl-N-dithiocarboxyglucamine significantly lowers the Cd content of both the liver and kidney, which is organs most susceptible to Cd-induced toxicity .

HY-B0579

Cyclosporin A Maximum Cited Publications 122 Publications Verification Cyclosporine A; Ciclosporin A; CsA	Structural Classification Natural Products Microorganisms Classification of Application Fields Anti-aging Source classification Inflammation/Immunology Disease Research Fields Cancer	Molecular Glues Complement System Antibiotic Cyclophilin
Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC₅₀ of 5 nM ^[3]. Cyclosporin A also inhibits *CD11a/CD18* adhesion .

HY-N3829

epi-Eudesmol	Structural Classification Terpenoids Sesquiterpenes Source classification Erythrina burttii Baker f. Plants Compositae	Others
epi-Eudesmol is a Sesquiterpenoids product that can be isolated from the leaves of Laggera alata var. montana C. D. Adams. .

HY-N10445

Maydispenoid A	Structural Classification Microorganisms Terpenoids Sesquiterpenes Source classification Plants Salicaceae	CD28 CD3
Maydispenoid A is a potent immunosuppressor. Maydispenoid A can inhibit anti-CD3/anti-CD28 mAbs activated and lipopolysaccharide activated murine splenocyte proliferation .

HY-111054

N-methyl-N-dithiocarboxyglucamine MDCG	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
N-methyl-N-dithiocarboxyglucamine (MDCG) mobilizes and promotes excretion of metallothione-bound ¹⁰⁹Cd. N-methyl-N-dithiocarboxyglucamine shows effects on acute and chronic Cd intoxication .

HY-W020790

Sialyl-Lewis X sLeX	Structural Classification Polysaccharides Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields Saccharides	Endogenous Metabolite
Sialyl-Lewis X (sLeX) is a sialylated fucosylated tetrasaccharide, an endogenous antigen. Sialyl-Lewis X is a high-affinity ligand for selectins (E-, P-, and L-selectin) . Sialyl-Lewis X binds to ELAM-1 and CD62 and has the ability?to inhibits CD62-mediated neutrophil recruitment to sites of inflammation .

HY-B0579R

Cyclosporin A (Standard)	Structural Classification Natural Products Microorganisms Source classification	Molecular Glues Complement System Antibiotic Cyclophilin
Cyclosporin A (Standard) is the analytical standard of Cyclosporin A. This product is intended for research and analytical applications. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM ^[3]. Cyclosporin A also inhibits CD11a/CD18 adhesion .

HY-N10446

Maydispenoid B	Structural Classification Microorganisms Terpenoids Sesquiterpenes Source classification	CD28 CD3
Maydispenoid B is a potent immunosuppressor. Maydispenoid B can inhibit anti-CD3/anti-CD28 mAbs activated and lipopolysaccharide activated murine splenocyte proliferation .

HY-B0430B

(±)-Pantothenic acid (±)-Pantothenate; (±)-Vitamin B5	Other disease Disease markers Endogenous metabolite	Endogenous Metabolite
(±)-Pantothenic acid ((±)-Pantothenate), a B-vitamin, is an essential vitamin required for the biosynthesis of coenzyme A (CoA) in mammalian cells. Pantothenic acid has protective activity against valproic acid (VPA)-induced neural tube defects (NTD) in CD-1 mice .

HY-106784

Ajoene	Infection Natural Products Liliaceae Classification of Application Fields Source classification Plants Disease Research Fields A．Sativam L. var．Viviparum Regel	Fungal Apoptosis
Ajoene, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities .

HY-N1115

Tubotaiwine (+)-Tubotaiwine; NSC 306222; Tubotaiwin	Apocynaceae Structural Classification Alkaloids Other Alkaloids Source classification Hunteria zeylanica Plants	Others
Tubotaiwine ((+)-Tubotaiwine), an alkaloid, has beneficial effect on cadmium (Cd) induced hypertension in rats. Tubotaiwine regulates systolic, diastolic and mean arterial blood pressure of the Cd exposed rats. Tubotaiwine reduces arterial stiffness, inhibits of oxidative stress and increases vascular remodeling .

HY-B0134A

Bestatin hydrochloride 5+ Cited Publications Ubenimex hydrochloride	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Aminopeptidase Bacterial Antibiotic
Bestatin hydrochloride is an inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase, used for cancer research.

HY-B0134B

Bestatin trifluoroacetate Ubenimex trifluoroacetate	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Aminopeptidase Bacterial Antibiotic
Bestatin trifluoroacetate is an inhibitor of CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase, used for cancer research.

HY-B0134

Bestatin 5+ Cited Publications Ubenimex	Infection Structural Classification Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease Research Fields	Aminopeptidase Bacterial Antibiotic
Bestatin is a natural, broad-spectrum, and competitive CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase inhibitor. Bestatin has anticancer effects .

HY-N2362

DL-Alanine DL-2-Aminopropionic acid	Structural Classification Human Gut Microbiota Metabolites Classification of Application Fields Source classification Metabolic Disease Amino acids Endogenous metabolite Disease Research Fields	Endogenous Metabolite
DL-alanine, an orally active amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver ^[3] .

HY-N2940

Bisandrographolide A BAA	Structural Classification Andrographis paniculata (Burm. F.) Nees Acanthaceae Terpenoids Source classification Diterpenoids Plants	TRP Channel
Bisandrographolide A (BAA) activates TRPV4 channel with an EC₅₀ of 790-950 nM. Bisandrographolide A can bind to CD81 and suppress its function. Bisandrographolide A is an anti-inflammatory, immunostimulant, and antihypertensive compound .

HY-N2109

Macranthoidin A	Triterpenes Structural Classification Caprifoliaceae Classification of Application Fields Terpenoids Source classification Metabolic Disease Plants Disease Research Fields	Others
Macranthoidin A is an orally active saponin from Flos Lonicerae. Macranthoidin A possess protection effects on hepatic injury caused by Acetaminophen, Cd, and CCl4, and conspicuous depressant effects on swelling of ear croton oil .

HY-N0640

Kuromanin chloride 5+ Cited Publications Chrysontemin; Cyanidin 3-O-glucoside chloride	Structural Classification Classification of Application Fields Source classification Metabolic Disease Plants Moraceae Anthocyans Flavonoids Microorganisms Phenols Polyphenols Disease Research Fields Morus alba Linn.	CD38
Kuromanin chloride (Chrysontemin) is derived from mulberry leaves and has the effect of increasing blood sugar concentration and maintaining lipid metabolism balance to reduce obesity. Kuromanin chloride can inhibit CD38 enzymatic activities ^[3].

HY-B0134R

Bestatin (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Aminopeptidase Bacterial Antibiotic
Bestatin (Standard) is the analytical standard of Bestatin. This product is intended for research and analytical applications. Bestatin is a natural, broad-spectrum, and competitive CD13 (Aminopeptidase N)/APN and leukotriene A4 hydrolase inhibitor. Bestatin has anticancer effects .

HY-N12613

Sydowimide A	Structural Classification Natural Products Microorganisms Marine natural products Source classification Marine microorganism	Phosphatase
Sydowimide A is a potent inhibitor of Src homology region 2 domain-containing phosphatase-1 (SHP1), T-cell protein tyrosine phosphatase (TCPTP) and leukocyte common antigen (CD45), with IC₅₀ values of 1.5, 2.4 and 18.83 μM, respectively .

HY-N2109R

Macranthoidin A (Standard)	Triterpenes Structural Classification Caprifoliaceae Terpenoids Source classification Plants	Others
Macranthoidin A (Standard) is the analytical standard of Macranthoidin A. This product is intended for research and analytical applications. Macranthoidin A is an orally active saponin from Flos Lonicerae. Macranthoidin A possess protection effects on hepatic injury caused by Acetaminophen, Cd, and CCl4, and conspicuous depressant effects on swelling of ear croton oil .

HY-N0640R

Kuromanin chloride (Standard)	Structural Classification Anthocyans Flavonoids Microorganisms Source classification Phenols Polyphenols Plants Moraceae Morus alba Linn.	CD38
Kuromanin (chloride) (Standard) is the analytical standard of Kuromanin (chloride). This product is intended for research and analytical applications. Kuromanin chloride (Chrysontemin) is derived from mulberry leaves and has the effect of increasing blood sugar concentration and maintaining lipid metabolism balance to reduce obesity. Kuromanin chloride can inhibit CD38 enzymatic activities ^[3].

HY-119347

Cirsilineol 2 Publications Verification	Laburnum anagyroides Medic. Structural Classification Monophenols Flavonoids Classification of Application Fields Flavones Source classification Phenols Plants Compositae Inflammation/Immunology Disease Research Fields	IFNAR STAT
Cirsilineol, a natural flavone compound, selectively inhibits IFN-γ/STAT1/T-bet signaling in intestinal CD4 ⁺ T cells. Cirsilineol has potent immunosuppressive and anti-tumor properties. Cirsilineol significantly ameliorates trinitro-benzene sulfonic acid (TNBS)-induced T-cell-mediated experimental colitis in mice .

HY-N9965

2'-Fucosyllactose 2'-FL	Infection Structural Classification Polysaccharides Animals Classification of Application Fields Inflammation/Immunology Disease Research Fields Saccharides	TNF Receptor Interleukin Related
2'-Fucosyllactose (2'-FL) is an oligosaccharide that could be derived from human milk. 2'-Fucosyllactose regulates the expression of CD14, alleviates colitis and regulates the gut microbiome. 2'-Fucosyllactose stimulates T cells to increase IFN-γ production and decreases IL-6, IL-17, and TNF-α production of cytokines .

HY-15310

Ivermectin 20+ Cited Publications MK-933; CD-5024; K-237	Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Antiviral Anti-parasitic Disease Research Disease Research Fields Cancer	Flavivirus Dengue virus Parasite HIV Mitophagy HSV SARS-CoV Antibiotic Autophagy Bacterial
Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin (MK-933) is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. It is a positive allosteric effector of P2X₄ and the α7 neuronal nicotinic acetylcholine receptor (nAChRs). Ivermectin also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import ^[3] . Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 .

HY-116003

12,13-DiHOME	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
12,13-DiHOME is a stimulator of Brown adipose tissue (BAT), as well as a thermogenic lipokine that activates BAT in response to cold. (±)12,13-DiHOME activates BAT fuel uptake and enhances cold tolerance, via promoting the translocation of the FA transporters FATP1 and CD36 to the cell membrane. (±)12,13-DiHOME can be used for research of metabolic disorders .

HY-107780

Cyclic-di-GMP c-di-GMP; cyclic diguanylate; 5GP-5GP	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	STING Endogenous Metabolite
Cyclic-di-GMP is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP can be used in cancer research ^[3] .

HY-107780A

Cyclic-di-GMP sodium c-di-GMP sodium; cyclic diguanylate sodium; 5GP-5GP sodium	Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	STING Endogenous Metabolite
Cyclic-di-GMP sodium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP sodium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP sodium can be used in cancer research ^[3] .

HY-119347R

Cirsilineol (Standard)	Laburnum anagyroides Medic. Structural Classification Monophenols Flavonoids Flavones Source classification Phenols Plants Compositae	IFNAR STAT
Cirsilineol (Standard) is the analytical standard of Cirsilineol. This product is intended for research and analytical applications. Cirsilineol, a natural flavone compound, selectively inhibits IFN-γ/STAT1/T-bet signaling in intestinal CD4+ T cells. Cirsilineol has potent immunosuppressive and anti-tumor properties. Cirsilineol significantly ameliorates trinitro-benzene sulfonic acid (TNBS)-induced T-cell-mediated experimental colitis in mice .

HY-N0743

Senkyunolide A 2 Publications Verification	Structural Classification Natural Products Classification of Application Fields Source classification Dicerothamnus rhinocerotis Umbelliferae Plants Disease Research Fields Cancer	Lactate Dehydrogenase α-synuclein Apoptosis Caspase Interleukin Related Phosphatase NOD-like Receptor (NLR)
Senkyunolide A is a phthalein compound. Senkyunolide A inhibits the proliferation of tumor cells and has anticancer activity. Senkyunolide A inhibits the progression of osteoarthritis through the NLRP3 signaling pathway. Senkyunolide A protects nerve cells from Corticosterone (HY-B1618) -induced apoptosis by regulating protein phosphatase 2A and α-synuclein signaling pathways. Senkyunolide A inhibits the expression of CD137, a diagnostic biomarker for atherosclerosis ^[3] .

HY-129997

Luteolinidin chloride	Structural Classification Anthocyans Flavonoids Sorghum bicolor (Linn.) Moench Classification of Application Fields Gramineae Source classification Phenols Polyphenols Plants Inflammation/Immunology Disease Research Fields	CD38 NADPH Oxidase Tyrosinase
Luteolinidin chloride is a deoxyanthocyanidin isolated from the plant Sorghum bicolor with antioxidant activity. Luteolinidin chloride is a potent *CD38* inhibitor (K_i=11.4 μM) and protects the heart from ischemia/reperfusion injury by preserving endothelial nitric oxide synthase (eNOS) function and preventing endothelial dysfunction. Luteolinidin chloride is also a competitive inhibitor of tyrosinase (IC₅₀=3.7 μM) and blocks the production of melanin ^[3] .

HY-N9481

Lipoteichoic acid	Structural Classification Natural Products Microorganisms Classification of Application Fields Source classification Inflammation/Immunology Disease Research Fields	Complement System Autophagy mTOR Akt PI3K ERK Interleukin Related
Lipoteichoic acid is an orally effect anti-inflammatory and antitumor agent. Lipoteichoic acid is a crucial immune molecule in Gram-positive bacteria that activates the complement system by inducing C3 and inhibiting *CD55. Lipoteichoic acid regulates macrophage autophagy through the PI3K/Akt/mTOR* pathway. Lipoteichoic acid induces lung damage in mice. Lipoteichoic acid inhibits the production of melanin ^[3] .

HY-107780B

Cyclic-di-GMP diammonium 5 Publications Verification c-di-GMP diammonium; cyclic diguanylate diammonium; 5GP-5GP diammonium	Structural Classification Natural Products Classification of Application Fields Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	STING Endogenous Metabolite
Cyclic-di-GMP diammonium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP diammonium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP diammonium can be used in cancer research ^[3] .

Cat. No.	Product Name	Chemical Structure

HY-N0898S

Catechin-13C3
Catechin- ¹³C₃ is the ¹³C-labeled Catechin. Catechin ((+)-Catechin) inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM.

HY-40354S

Tofacitinib-13C3
Tofacitinib- ¹³C₃ is the ¹³C-labeled Tofacitinib. Tofacitinib is an orally available JAK3/2/1 inhibitor with IC50s of 1, 20, and 112 nM, respectively.

HY-A0253S

Cefacetrile-13C3
Cefacetrile- ¹³C₃ is the ¹³C₃ labeled Cefacetrile.

HY-B0234S

Estrone-13C3
Estrone- ¹³C₃ is the ¹³C-labeled Estrone. Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].

HY-B1331S1

Cyromazine-13C3
Cyromazine- ¹³C₃ is the ¹³C₃ labeled Cyromazine. Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects.

HY-100196S1

Pyrroloquinoline quinone-13C3 sodium
Pyrroloquinoline quinone-13C3 (sodium) is an isotope of Pyrroloquinoline quinone. Pyrroloquinoline quinone (PQQ), a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone is an essential nutrient for mammals and is important for immune function .

HY-B1804S

Tricaprilin-13C3
Tricaprilin-13C3 is a deuterated labeled Tricaprilin . Tricaprilin (Trioctanoin) is used in study for patients with mild to moderate Alzheimer's disease and has a role as an anticonvulsant and a plant metabolite ^[3].

HY-W653853

Ritonavir-13C3
Ritonavir- ¹³C₃ is ¹³C labeled Ritonavir. Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CL ^pro inhibitor with an IC₅₀ of 1.61 μM .

HY-B0389S18

D-Glucose-13C3-1
D-Glucose- ¹³C₃-1 is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-B0389S9

D-Glucose-13C3-2
D-Glucose- ¹³C₃-2 is the ¹³C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical signaling molecules in relation to both cellular metabolic status and biotic and abiotic stress response[1].

HY-W654126

Cytarabine-13C3
Cytarabine- ¹³C₃ (Cytosine β-D-arabinofuranoside- ¹³C₃) is ¹³C labeled Cytarabine .

HY-100532S

CD437-13C6
CD437- ¹³C₆ is the ¹³C- and deuterium labeled CD437. CD437 is a selective Retinoic Acid Receptor γ (RARγ) agonist.

HY-N0650S

L-Serine-13C3
L-Serine- ¹³C₃ is the ¹³C-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-B0495S4

Lamotrigine-13C3
Lamotrigine- ¹³C₃ is the ¹³C-labeled Lamotrigine. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al[1][2].

HY-N0680S3

Thiamine-13C3 hydrochloride
Thiamine- ¹³C₃ (hydrochloride) is the ¹³C-labeled Thiamine (hydrochloride). Thiamine hydrochloride (Thiamine chloride hydrochloride) is an essential micronutrient needed as a cofactor for many central metabolic enzymes.

HY-14605S

Rasagiline-13C3 mesylate
Rasagiline- ¹³C₃ ((R)-AGN1135- ¹³C₃; TVP1012- ¹³C₃) mesylateis the deuterium labeledRasagiline (mesylate)(HY-14605) . Rasagiline (R-AGN1135) mesylate is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC₅₀s of 4.43?nM and 412?nM for rat brain MAO B and A activity, respectively .

HY-Y0921S3

(±)-1,2-Propanediol-13C3
(±)-1,2-Propanediol- ¹³C₃ is ¹³C labeled (±)-1,2-Propanediol (HY-Y0921). (±)-1, 2-propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol that is often used as an excipient in many active molecular preparations to increase the solubility and stability of the active molecule. (±)-1, 2-propanediol can affect the neurobehavior of zebrafish .

HY-14605BS

Rasagiline-13C3 mesylate racemic

Rasagiline- ¹³C₃ (mesylate racemic) is a ¹³C-labeled Rasagiline mesylate racemic. Rasagiline mesylate racemic is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor[1]. Rasagiline-13C3 (mesylate racemic) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0891S1

17α-Hydroxyprogesterone-13C3
17α-Hydroxyprogesterone- ¹³C₃ is the ¹³C-labeled 17α-Hydroxyprogesterone. 17α-Hydroxyprogesterone (17-Hydroxyprogesterone) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.

HY-N0086S3

N6-Methyladenosine-13C3
N6-Methyladenosine- ¹³C₃ (6-Methyladenosine- ¹³C₃) is ¹³C-labeled N6-Methyladenosine (HY-N0086). N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities ^[3].

HY-W777148

Anagrelide-13C3
Anagrelide- ¹³C₃ (BL 4162A- ¹³C₃) is ¹³C labeled Anagrelide .

HY-D0184S3

2'-Deoxycytidine-13C9,15N3
2'-Deoxycytidine- ¹³C₉, ¹⁵N₃ (Deoxycytidine- ¹³C₉, ¹⁵N₃; Cytosine deoxyriboside- ¹³C₉, ¹⁵N₃; Deoxyribose cytidine- ¹³C₉, ¹⁵N₃) is ¹³C and ¹⁵N-labeled 2'-Deoxycytidine (HY-D0184). 2'-Deoxycytidine, a deoxyribonucleoside, could inhibit biological effects of Bromodeoxyuridine (Brdu).

HY-113008AS

cis-Urocanic acid-13C3
cis-Urocanic acid- ¹³C₃ is the ¹³C-labeled cis-Urocanic acid. cis-Urocanic acid is a 5-HT2A receptor agonist. cis-Urocanic acid binds to 5-HT receptor with relatively high affinity (Kd=4.6 nM). cis-Urocanic acid is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor[1].

HY-B1342S3

Vitamin A-13C3
Vitamin A- ¹³C₃ (Vitamin A1- ¹³C₃; all-trans-Retinol- ¹³C₃) is a ¹³C-labeled Vitamin A/Vitamin A (HY-B1342). Vitamin A is an endogenous metabolite.

HY-N0610AS2

Cinnamic acid-13C3
Cinnamic acid- ¹³C₃ (3-Phenylacrylic acid- ¹³C₃) is the ¹³C labeled Cinnamic acid (HY-N0610A). Cinnamic acid has potential use in cancer intervention, with IC₅₀s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells .

HY-18569S4

3-Indoleacetic acid-13C6
3-Indoleacetic acid- ¹³C₆ is the ¹³C labeled 3-Indoleacetic acid[1]. 3-Indoleacetic acid (Indole-3-acetic acid) is the most common natural plant growth hormone of the auxin class. It can be added to cell culture medium to induce plant cell elongation and division .

HY-W768345

D-(+)-Trehalose-13C12
D-(+)-Trehalose-13C12 is a ¹³C isotope labeled version of D-(+)-Trehalose (HY-N1132). D-(+)-Trehalose,which is widespread, can be used as a food ingredient and pharmaceutical excipient .

HY-110382S

13C20,15N10-Cyclic di-GMP sodium

¹³C20, ¹⁵N10-Cyclic di-GMP ( ¹³C20, ¹⁵N10-c-di-GMP) is ¹³C and ¹⁵N labeled Cyclic-di-GMP (disodium). Cyclic-di-GMP disodium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP disodium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP disodium can be used in cancer research ^[3] .

HY-Y0721S

3-Bromofluorobenzene-13C6
3-Bromofluorobenzene- ¹³C₆ is the ¹³C labeled 3-Bromofluorobenzene[1].

HY-N0304S1

L-DOPA-13C6
L-DOPA- ¹³C₆ is the ¹³C-labled L-DOPA . L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease ^[3] .

HY-Y0219S

1,2,4-Triazole-13C2,15N3
NSC 83128- ¹³C₂, ¹⁵N₃ is the ¹³C and ¹⁵N labeled NSC 83128[1].

HY-B0150S1

Nicotinamide-15N,13C3
Nicotinamide- ¹⁵N, ¹³C₃ is the ¹³C-labeled and ¹⁵N-labeled Nicotinamide. Nicotinamide is a form of vitamin B3 that plays essential roles in cell physiology through facilitating NAD+ redox homeostasis and providing NAD+ as a substrate to a class of enzymes that catalyze non-redox reactions. Nicotinamide is an inhibitor of SIRT1.

HY-B0412S3

Estriol-13C3
Estriol- ¹³C₃ is the ¹³C-labeled Estriol. Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells.

HY-B1659S5

Glycerol-13C3
Glycerol- ¹³C₃ is the ¹³C labeled Glycerol[1]. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis[2][3][4].

HY-N0136S1

(±)-Taxifolin-13C3

(±)-Taxifolin-13C3 ((±)-Dihydroquercetin-13C3) is a derivative of (±)-Taxifolin, labeled with 13C3. (±)-Taxifolin is the racemate of Taxifolin. Taxifolin exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC₅₀ value of 193.3 μM . Taxifolin is an important natural compound with antifibrotic activity. Taxifolin is a free radical scavenger with antioxidant capacity .

HY-B0111RS

Drospirenone-13C3
Drospirenone- ¹³C₃ is ¹³C labeled Drospirenone. Drospirenone (Dihydrospirorenone) is a synthetic progesterone that is an analog of Spironolactone .

HY-Y0589S

m-Cyanobenzoic acid-13C6
m-Cyanobenzoic acid- ¹³C₆ is the ¹³C labeled m-Cyanobenzoic acid[1].

HY-B0178AS

Guanidine-13C,15N3 hydrochloride
Guanidine- ¹³C, ¹⁵N₃ (hydrochloride)is the ¹³C-labeled and ¹⁵N-labeled Guanidine hydrochloride. Guanidine hydrochloride (Guanidinium chloride) a strong chaotrope, is also a strong denaturant of proteins[1][2].

HY-N0650S5

L-Serine-13C3,15N
L-Serine- ¹³C₃, ¹⁵N is the ¹³C- and ¹⁵N-labeled L-Serine. L-Serine ((-)-Serine; (S)-Serine), one of the so-called non-essential amino acids, plays a central role in cellular proliferation.

HY-W015913S

Sodium 2-oxopropanoate-13C3
Sodium 2-oxopropanoate- ¹³C₃ is the ¹³C-labeled Sodium 2-oxopropanoate. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS[1][2].

HY-139145S

Etbicyphat-13C3
Etbicyphat- ¹³C₃ is the ¹³C labeled Etbicyphat (HY-139145). Etbicyphat is a potent GABA(A) receptors competitive antagonist. Etbicyphat induces epileptiform activities in hippocampal CA1 neurons, and binds to the GABA(A)-benzodiazepine receptors[1][2].

HY-12542S

Dantrolene-13C3

Dantrolene- ¹³C₃ is the ¹³C₃ labeled Dantrolene. Dantrolene (F368), a muscle relaxant, non-competitively inhibits human erythrocyte glutathione reductase. Ki and IC50 values are 111.6 μM and 52.3 μM, respectively. Dantrolene is a ryanodine receptor antagonist and Ca2+ signaling stabilizer. Dantrolene can be used for the research of muscle spasticity, malignant hyperthermia, Huntington's disease and other neuroleptic malignant syndrome.

HY-W769714

Favipiravir-13C3
Favipiravir- ¹³C3 is the ¹³C labeled isotope of Favipiravir- ¹³C3(HY-14768 ).Favipiravir (T-705) is a potent viral RNA polymerase inhibitor, it is phosphoribosylated by cellular enzymes to its active form, Favipiravir-ribofuranosyl-5′-triphosphate (RTP). Favipiravir-RTP inhibits the influenza viral RNA-dependent RNA polymerase (RdRP) activity with an IC₅₀ of 341 nM.

HY-127035S1

Tristearin-13C3
Tristearin- ¹³C₃ (Glycerol tristearate- ¹³C₃) is ¹³C labeled Tristearin. Tristearin is a triglyceride derived from three units of stearic acid .

HY-15306S

Eltrombopag-13C4

1 Publications Verification

Eltrombopag- ¹³C₄ (SB-497115- ¹³C₄) is ^{13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus (Staphylococcus aureus) and can induce apoptosis (apoptosis) in liver cancer cells ^[3] .}

HY-B0158S5

Cytidine-13C9,15N3
Cytidine- ¹³C₉, ¹⁵N₃ is the ¹³C and ¹⁵N labeled Cytidine[1]. Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function[2][3][4].

HY-W009162S5

Cytidine 5′-monophosphate-13C9,15N3 dilithium

Cytidine 5′-monophosphate- ¹³C₉, ¹⁵N₃ (5'-Cytidylic acid- ¹³C₉, ¹⁵N₃ dilithium; 5'-CMP- ¹³C₉, ¹⁵N₃) dilithium is ¹³C and ¹⁵N-labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.

HY-101400S2

Deoxycytidine triphosphate-13C9,15N3 dilithium

Deoxycytidine triphosphate- ¹³C₉, ¹⁵N₃ (dCTP- ¹³C₉, ¹⁵N₃ dilithium; 2′-Deoxycytidine-5′-triphosphate- ¹³C₉, ¹⁵N₃) dilithium is ¹³C and ¹⁵N-labeled Deoxycytidine triphosphate (HY-101400). Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.

HY-Y1088S

Hydrocinnamic acid-2,3-13C2
Hydrocinnamic acid-2,3- ¹³C₂ is the ¹³C-labeled Hydrocinnamic acid. Hydrocinnamic acid is the major rhizospheric compound with known growth regulatory activities.

HY-N0230S

β-Alanine-13C3,15N
β-Alanine- ¹³C₃, ¹⁵N is the ¹³C- and ¹⁵N-labeled β-Alanine. β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Species:	Human (1219) Rhesus Macaque (143) Rat (217) Bovine (2) Cynomolgus (239) E.coli (2) Rabbit (12) Canine (50) Pig (1) Rhesus Macaque/Cynomolgus (1) Marmoset (2) Mouse (467) Dog (1)
Tag:	SUMO (17) GST (21) Flag (51) GFP (4) His (1549) Strep (7) Tag Free (88) Avi (381) Myc (15) HSA (1) MBP (1) Trx (5) Fc (733) B2M (1)
Source:	HEK293 (2155) E. coli Cell-free (7) CHO (6) CHO (9) Sf9 insect cells (3) P. pastoris (19) Sf9 insect cells (50) E. coli (86)


Products	In-stock - + Add to Cart
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote


Products	In-stock - + Add to Cart
Cat. No.
Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
Isotype
Gene ID
SwissProt ID
Purity
Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

NBI-56418-<sup>13</sup>C,d<sub>3</sub>

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

NaturalProducts

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Oligonucleotides

Natural
Products