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NO-711

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-103506
    NNC-711

    NO-711 hydrochloride

    		 GABA Receptor Neurological Disease
    NNC-711 (NO-711 hydrochloride) is a potent and selective inhibitor of GAT-1 (GABA transporter 1) with IC50 values of 0.04, 0.38, 171, 1700, 349, 622 μM for human GAT-1, rat GAT-1, rGAT-2, hGAT-3, rGAT-3, hBGT-3, respectively. NNC-711 has anticonvulsant and analgesic effect in vivo and exhibits cognition-enhancing activity .
    NNC-711
  • HY-114040
    NO-711

    NNC-711 free acid

    		 GABA Receptor Neurological Disease
    NO-711 (NNC-711) free acid is a novel potent and selective inhibitor of γ-aminobutyric acid uptake. NO-711 inhibits synaptosomal (IC50 = 47 nM), neuronal (IC50 = 1238 nM) and glial (IC50 = 636 nM) GABA uptake in vitro .
    NO-711
  • HY-129464
    NO-711ME

    		GABA Receptor Neurological Disease
    NO-711ME is a prodrug of NO-711. NO-711 is a potent and selective GABA uptake inhibitor .
    NO-711ME

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