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NOP1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) IKK (1) Opioid Receptor (3) STAT (1)
By Research Areas:	Cancer (1) Inflammation/Immunology (3) Neurological Disease (1)

4

Inhibitors & Agonists

2

Peptides

1

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

AT-076	Opioid Receptor	Neurological Disease
AT-076 is an opioid pan antagonist at nociception, kappa, mu, and delta opioid receptors, with K_i values of 1.75 nM (NOP), 1.67 nM (MOP), 1.14 nM (KOP) and 19.6 nM (DOP), respectively ^[1] .

Nociceptin(1-7)	Opioid Receptor	Inflammation/Immunology
Nociceptin (1-7) is the N-terminal bioactive fragment of nociceptin (HY-P0183). Nociceptin (1-7) is a potent *ORL₁ (NOP)* receptor agonist with antinociceptive activity. Nociceptin (1-7) combines with nociceptin reduces hyperalgesia in vivo ^[1].

Nociceptin(1-7) TFA	Opioid Receptor	Inflammation/Immunology
Nociceptin (1-7) TFA is the N-terminal bioactive fragment of nociceptin (HY-P0183). Nociceptin (1-7) TFA is a potent *ORL₁ (NOP)* receptor agonist with antinociceptive activity. Nociceptin (1-7) TFA combines with nociceptin reduces hyperalgesia in vivo ^[1].

ACHP	IKK STAT Apoptosis	Inflammation/Immunology Cancer
ACHP (compound 4j) is a selective and orally active IκB kinase inhibitor with IC₅₀ values of 8.5 nM and 250 nM for IKKβ and IKKα, respectively. ACHP can effectively inhibit the STAT3 signaling pathway and induce cancer cell cycle arrest and apoptosis. ACHP shows anti-inflammatory activity in a mouse ear edema model. ACHP can be used in anti-inflammatory and anti-cancer (such as multiple myeloma and leukemia) studies ^[1] .

Cat. No.	Product Name	Target	Research Area

Nociceptin(1-7)	Opioid Receptor	Inflammation/Immunology
Nociceptin (1-7) is the N-terminal bioactive fragment of nociceptin (HY-P0183). Nociceptin (1-7) is a potent *ORL₁ (NOP)* receptor agonist with antinociceptive activity. Nociceptin (1-7) combines with nociceptin reduces hyperalgesia in vivo ^[1].

Nociceptin(1-7) TFA	Opioid Receptor	Inflammation/Immunology
Nociceptin (1-7) TFA is the N-terminal bioactive fragment of nociceptin (HY-P0183). Nociceptin (1-7) TFA is a potent *ORL₁ (NOP)* receptor agonist with antinociceptive activity. Nociceptin (1-7) TFA combines with nociceptin reduces hyperalgesia in vivo ^[1].

Cat. No.	Compare	Product Name	Application	Reactivity

	Fibrillarin Antibody FIB; FLRN; NOP1; RNU3IP1	WB, IP	Human, Mouse, Rat
	Fibrillarin Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 34 kDa, targeting to Fibrillarin. It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat.

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