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Results for "

NSC 745887

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Caspase (1)
By Research Areas:	Cancer (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

*NSC745887*	Apoptosis Caspase	Cancer
NSC745887 (compound 25) is an inhibitor that targets DNA topoisomerase cleavage, activates the caspase-8/9-caspase-3-poly (ADP-ribose) polymerase cascade, and induces apoptosis in cancer cells. NSC745887 enhances γH2AX expression and causes DNA fragmentation leading to DNA damage .

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