1. Search Result
Search Result
Results for "

Nicotinic acid (standard)

" in MedChemExpress (MCE) Product Catalog:

37

Inhibitors & Agonists

1

Biochemical Assay Reagents

23

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0150R
    Nicotinamide (Standard)
    Maximum Cited Publications
    49 Publications Verification

    Niacinamide(standard); Nicotinic acid amide (standard)

    Endogenous Metabolite Sirtuin Cancer
    Nicotinamide (Standard) is the analytical standard of Nicotinamide. This product is intended for research and analytical applications. Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity .
    Nicotinamide (Standard)
  • HY-B0143R

    Nicotinic acid (standard); Vitamin B3 (standard)

    Autophagy Endogenous Metabolite Cardiovascular Disease Metabolic Disease Cancer
    Niacin (Standard) is the analytical standard of Niacin. This product is intended for research and analytical applications. Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases .
    Niacin (standard)
  • HY-W004515R

    Endogenous Metabolite Others
    3-Pyridylacetic acid (hydrochloride) (Standard) is the analytical standard of 3-Pyridylacetic acid (hydrochloride). This product is intended for research and analytical applications. 3-Pyridineacetic acid hydrochloride is a higher homologue of nicotinic acid, a breakdown product of nicotine (and other tobacco alkaloids) .
    3-Pyridylacetic acid hydrochloride (Standard)
  • HY-W040430R

    Endogenous Metabolite Others
    (S)-Nornicotine (Standard) is the analytical standard of (S)-Nornicotine. This product is intended for research and analytical applications. (S)-Nornicotine is a metabolite of nicotine.
    (S)-Nornicotine (Standard)
  • HY-W002112R

    Endogenous Metabolite Drug Metabolite Neurological Disease
    (±)-Nornicotine (Standard) is the analytical standard of (±)-Nornicotine. This product is intended for research and analytical applications. (±)-Nornicotine is the primary metabolite of nicotine that is formed through demethylation of nicotine in the genus Nicotiana tabacum L. (±)-Nornicotine is a precursor of tobacco-specific nitrosamine N-nitrosonornicotine. (±)-Nornicotine has detrimental effects to human health .
    (±)-Nornicotine (Standard)
  • HY-145297R

    nAChR Neurological Disease
    Flupyrimin (Standard) is the analytical standard of Flupyrimin. This product is intended for research and analytical applications. Flupyrimin acts as an antagonist at the insect nicotinic acetylcholine receptor (nAChR) .
    Flupyrimin (Standard)
  • HY-B1178R

    Endogenous Metabolite nAChR Cardiovascular Disease Inflammation/Immunology
    Cotinine (Standard) is the analytical standard of Cotinine. This product is intended for research and analytical applications. Cotinine ((-)-Cotinine), an alkaloid in tobacco and a major metabolite of nicotine, is used as a biological indicator to measure the composition of tobacco smoke
    Cotinine (Standard)
  • HY-14774R

    nAChR Cancer
    Monepantel (Standard) is the analytical standard of Monepantel. This product is intended for research and analytical applications. Monepantel is organic anthelmintic, and acts as a positive allosteric modulator of a nematode-specific clade of nicotinic acetylcholine receptor (nAChR) subunits.
    Monepantel (Standard)
  • HY-N0443R

    nAChR Inflammation/Immunology
    N-Methylcytisine (Standard) is the analytical standard of N-Methylcytisine. This product is intended for research and analytical applications. N-Methylcytisine (Caulophylline), a tricyclic quinolizidine alkaloid, exerts hypoglycaemic, analgesic and anti-inflammatory activities. N-methylcytisine is a selective ligand of nicotinic receptors of acetylcholine in the central nervous system and has a high affinity (Kd = 50 nM) to nicotinic acetylcholine receptors (nAChR) from squid optical ganglia .
    N-Methylcytisine (Standard)
  • HY-B1532R

    nAChR Neurological Disease
    Anabasine (Standard) is the analytical standard of Anabasine. This product is intended for research and analytical applications. Anabasine ((S)-Anabasine) is an alkaloid that found as a minor component in tobacco (Nicotiana). Anabasine is a botanical pesticide nicotine, acts as a full agonist of nicotinic acetylcholine receptors (nAChRs). Anabasine induces depolarization of TE671 cells endogenously expressing human fetal muscle-type nAChRs (EC50=0.7 μM) .
    Anabasine (Standard)
  • HY-B0823R

    nAChR Neurological Disease
    Acetamiprid (Standard) is the analytical standard of Acetamiprid. This product is intended for research and analytical applications. Acetamiprid is a neonicotinoid insecticide used worldwide. Acetamiprid is a nicotinic acetylcholine receptor (nAChR) agonist, and is shown to be associated with neuromuscular and reproductive disorders .
    Acetamiprid (Standard)
  • HY-B0942R

    nAChR Bacterial Neurological Disease
    Benzethonium (chloride) (Standard) is the analytical standard of Benzethonium (chloride). This product is intended for research and analytical applications. Benzethonium chloride inhibits nicotinic acetylcholine receptors in human recombinant α7 and α4β2 neurons in Xenopus laevis oocytes.
    Benzethonium chloride (Standard)
  • HY-W001909R

    nAChR Metabolic Disease
    Myosmine (Standard) is the analytical standard of Myosmine. This product is intended for research and analytical applications. Myosmine, a specific tobacco alkaloid in nuts and nut products, has low affinity for a4b2 nicotinic acetylcholinergic receptors (nAChR) with a Ki of 3300 nM .
    Myosmine (Standard)
  • HY-10021R

    nAChR ERK p38 MAPK Others Neurological Disease
    Varenicline (Tartrate) (Standard) is the analytical standard of Varenicline (Tartrate). This product is intended for research and analytical applications. Varenicline (CP 526555) is an orally active partial agonist of α4β2 nicotinic acetylcholine receptor (α4β2 nAChR, IC50 = 250 nM), which is the principal mediator of nicotine dependence. Varenicline is also a partial agonist of α6β2 nAChR and a full agonist of α6β2 nAChR. Varenicline blocks the direct agonist effects of nicotine on nAChR while stimulates nAChR in a more moderate way, being widely used as an aid of smoking cessation .
    Varenicline Tartrate (Standard)
  • HY-B0820R

    nAChR Parasite Neurological Disease
    Nitenpyram (Standard) is the analytical standard of Nitenpyram. This product is intended for research and analytical applications. Nitenpyram is a calss of neonicotinoid and an insect nicotinic acetylcholine receptor (nAChR) agonist with an IC50 of 14 nM. Nitenpyram is an oral fast-acting insecticide used to suppress sucking insects on companion animals .
    Nitenpyram (Standard)
  • HY-118614R

    Drug Metabolite Neurological Disease
    β-Nicotyrine (Standard) is the analytical standard of β-Nicotyrine. This product is intended for research and analytical applications. β-Nicotyrine is a metabolite of Nicotine.β-Nicotyrine, isolated from the leaves of Nicotiana tabacum plants and from cigarette smoke condensate, is a minor tobacco alkaloid .
    β-Nicotyrine (Standard)
  • HY-100806R
    Kynurenic acid (Standard)
    3 Publications Verification

    Quinurenic acid (standard)

    iGluR Endogenous Metabolite Apoptosis CXCR GPR35 Neurological Disease Inflammation/Immunology Endocrinology
    Kynurenic acid (Standard) is the analytical standard of Kynurenic acid. This product is intended for research and analytical applications. Kynurenic acid, an endogenous tryptophan metabolite, is a broad-spectrum antagonist targeting NMDA, glutamate, α7 nicotinic acetylcholine receptor. Kynurenic acid is also an agonist of GPR35/CXCR8.
    Kynurenic acid (Standard)
  • HY-B1337R

    nAChR Endogenous Metabolite Cancer
    Choline (chloride) (Standard) is the analytical standard of Choline (chloride). This product is intended for research and analytical applications. Choline chloride is an essential nutrient that activates alpha7 nicotinic receptors and has analgesic and anti-inflammatory activity. Glycerophosphoinositol choline can affect diseases such as liver disease, atherosclerosis and neurological disorders .
    Choline chloride (Standard)
  • HY-N0584AR

    mAChR Inflammation/Immunology
    Anisodamine (hydrobromide) (Standard) is the analytical standard of Anisodamine (hydrobromide). This product is intended for research and analytical applications. Anisodamine hydrobromide (6-Hydroxyhyoscyamine hydrobromide), a belladonna alkaloid, is a non-subtype-selective muscarinic and a nicotinic cholinoceptor antagonist. Anisodamine hydrobromide shows antioxidant, anti-inflammatory properties .
    Anisodamine hydrobromide (Standard)
  • HY-B0283R

    Others Metabolic Disease
    Acipimox (Standard) is the analytical standard of Acipimox. This product is intended for research and analytical applications. Acipimox (K-9321), a nicotinic acid analogue, is an antilipolytic compound. Acipimox stimulates leptin releas, inhibits lipolysis and suppresses systemic levels of free fatty acids (FFAs) and improves insulin sensitivity .
    Acipimox (Standard)
  • HY-B0118AR

    nAChR Neurological Disease Cancer
    Vecuronium (bromide) (Standard) is the analytical standard of Vecuronium (bromide). This product is intended for research and analytical applications. Vecuronium (ORG NC 45) bromide is a non-depolarizing neuromuscular blocking agent that also acts as a nicotinic acetylcholine receptor (nAChR) inhibitor, a muscle relaxant, and can be used for pre-surgical anesthesia .
    Vecuronium bromide (Standard)
  • HY-B0979R

    nAChR Dopamine Transporter Neurological Disease
    Lobeline (hydrochloride) (Standard) is the analytical standard of Lobeline (hydrochloride). This product is intended for research and analytical applications. Lobeline (α-Lobeline) hydrochloride is a brain-penetrant nicotinic receptor agonist. Lobeline hydrochloride increases dopamine (DA) release by inhibiting DA uptake into synaptic vesicles, and altering presynaptic DA storage. Lobeline hydrochloride is effective in smoking cessation .
    Lobeline hydrochloride (Standard)
  • HY-B0282R

    nAChR Calcium Channel Endogenous Metabolite Neurological Disease Cancer
    Acetylcholine (chloride) (Standard) is the analytical standard of Acetylcholine (chloride). This product is intended for research and analytical applications. Acetylcholine chloride (ACh chloride), a neurotransmitter, is a potent cholinergic agonist. Acetylcholine chloride is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs) . Acetylcholine chloride inhibits p53 mutant peptide aggregation in vitro .
    Acetylcholine chloride (Standard)
  • HY-B0461R

    mAChR Neurological Disease
    Trospium (chloride) (Standard) is the analytical standard of Trospium (chloride). This product is intended for research and analytical applications. Trospium chloride is an orally active, specific and competitive antagonist of muscarinic cholinergic receptors (mAChRs), with antimuscarinic activity. Trospium chloride binds to muscarinic receptors M1, M2 and M3 with high affinity, but not nicotinic, cholinergic receptors .
    Trospium chloride (Standard)
  • HY-B0489R

    mAChR nAChR Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
    Arecoline (hydrobromide) (Standard) is the analytical standard of Arecoline (hydrobromide). This product is intended for research and analytical applications. Arecoline hydrobromide, a naturally occurring psychoactive alkaloid, is a partial agonist of nicotinic and muscarinic acetylcholine receptor. Arecoline hydrobromide exhibits stimulation, alertness, anxiolysis and anti-parasitic effects. Arecoline hydrobromide also can induce oxidative stress .
    Arecoline (hydrobromide) (Standard)
  • HY-138800R

    nAChR Neurological Disease
    Spinosad (Standard) is the analytical standard of Spinosad. This product is intended for research and analytical applications. Spinosad, a mixture of spinosyns A and D known as fermentation products of a soil actinomycete (Saccharopolyspora spinosa), is a biological neurotoxic insecticide with a broader action spectrum. Spinosad targets the nicotinic acetylcholine receptor (nAChRs) of the insect nervous system. Spinosad has an excellent environmental and mammalian toxicological profile. Larvicidal activity .
    Spinosad (Standard)
  • HY-N1919R

    Adrenergic Receptor Cholinesterase (ChE) Neurological Disease Endocrinology
    Ajmalicine (Standard) is the analytical standard of Ajmalicine. This product is intended for research and analytical applications. Ajmalicine (Raubasine) is a potent adrenolytic agent which preferentially blocks α1-adrenoceptor. Ajmalicine is an reversible but non-competitive nicotine receptor full inhibitor, with an IC50 of 72.3 μM. Ajmalicine also can be used as anti-hypertensive, and serpentine, with sedative activity .
    Ajmalicine (Standard)
  • HY-12641R

    Parasite nAChR Antibiotic Infection
    Pyrantel (tartrate) (Standard) is the analytical standard of Pyrantel (tartrate). This product is intended for research and analytical applications. Pyrantel tartrate is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel tartrate can cause spasmodic muscle paralysis in parasites. Pyrantel tartrate can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis .
    Pyrantel tartrate (Standard)
  • HY-N7108R

    ERK Keap1-Nrf2 Inflammation/Immunology
    7-Hydroxyflavone (Standard) is the analytical standard of 7-Hydroxyflavone. This product is intended for research and analytical applications. 7-Hydroxyflavone is a flavonoid isolated from Clerodendrum phlomidis, with anti-inflammatory activity. 7-Hydroxyflavone protects renal cells from nicotine (NIC)-associated cytotoxicity via the ERK/Nrf2/HO-1 pathway .
    7-Hydroxyflavone (Standard)
  • HY-12640R

    Pyrantel embonate (standard)

    Parasite nAChR Antibiotic Infection
    Pyrantel (pamoate) (Standard) is the analytical standard of Pyrantel (pamoate). This product is intended for research and analytical applications. Pyrantel pamoate (Pyrantel embonate) is an orally active anthelmintic and an agonist of the nicotinic acetylcholine receptor (nAChR). Pyrantel pamoate can cause spasmodic muscle paralysis in parasites. Pyrantel pamoate can be used in the study of parasitic infections such as ascariasis, hookworm infections, intestinal worms (pinworm infections), trichinosis and trichinosis .
    Pyrantel pamoate (Standard)
  • HY-B1695R

    Others Cardiovascular Disease Inflammation/Immunology
    Methyl nicotinate (Standard) is the analytical standard of Methyl nicotinate. This product is intended for research and analytical applications. Methyl nicotinate (Nicotinic acid methyl ester) is an orally active vasodilator. Methyl nicotinate has analgesic activity. Methyl nicotinate causes local skin erythema when applied topically to the skin. Methyl nicotinate is used as an active ingredient in over-the-counter topical preparations for the study of muscle and joint pain .
    Methyl nicotinate (Standard)
  • HY-N1369R

    Calcium Channel Neurological Disease Cancer
    Menthol (Standard) is the analytical standard of Menthol. This product is intended for research and analytical applications. Menthol is an analgesic and TRPM8 modulator. TRPM8 is a cold temperature sensing ion channel, and Menthol can regulate TRPM8 to exert analgesic and anti-irritation mechanisms. Menthol stimulates cold receptors and produces a cooling sensation by inhibiting Ca++ currents in neuronal cell membranes. Menthol also improves oral nicotine rejection in mice .
    Menthol (Standard)
  • HY-126477R

    Endogenous Metabolite Cancer
    NNK (Standard) is the analytical standard of NNK. This product is intended for research and analytical applications. NNK is a nicotine-nitrosated derivative. NNK simultaneously stimulates Bcl2 phosphorylation exclusively at Ser70 and c-Myc at Thr58 and Ser62 through activation of both ERK1/2 and PKCα . NNK induces survival and proliferation of human lung cancer cells. NNK can be used for lung cancer mice model structure .
    NNK (Standard)
  • HY-B0379AR

    nAChR Neurological Disease
    Adiphenine (hydrochloride) (Standard) is the analytical standard of Adiphenine (hydrochloride). This product is intended for research and analytical applications. Adiphenine hydrochloride is a non-competitive inhibitor of nicotinic acetylcholine receptor (nAChR), with an IC50s of 1.9, 1.8, 3.7, and 6.3 μM for α1, α3β4, α4β2, and α4β4, respectively. Adiphenine hydrochloride has anticonvulsant effects .
    Adiphenine hydrochloride (Standard)
  • HY-W127670

    Biochemical Assay Reagents Others
    Decamethonium (iodide) is an organic compound containing ammonium and iodide ions. It is commonly used as a neuromuscular blocking agent in anesthesia to induce muscle relaxation during surgery. Decamethonium Iodide acts by binding to nicotinic acetylcholine receptors (nAChRs) in the neuromuscular junction, causing depolarization block and subsequent skeletal muscle paralysis. In addition, it can also serve as a reference standard for pharmacological studies of nAChRs.
    Decamethonium iodide
  • HY-A0009R

    Galantamine hydrobromide (standard)

    nAChR Cholinesterase (ChE) Neurological Disease
    Galanthamine (hydrobromide) (Standard) is the analytical standard of Galanthamine (hydrobromide). This product is intended for research and analytical applications. Galanthamine hydrobromide (Galantamine hydrobromide) is a selective, reversible, competitive, alkaloid AChE inhibitor, with an IC50 of 0.35 µM. Galanthamine hydrobromide is a potent allosteric potentiating ligand (APL) of human α3β4, α4β2, α6β4 nicotinic receptors ( nAChRs). Galanthamine hydrobromide is developed for the research of Alzheimer's disease (AD) .
    Galanthamine hydrobromide (Standard)
  • HY-15310R

    Dengue virus Flavivirus Parasite HIV Mitophagy HSV SARS-CoV Antibiotic Autophagy Bacterial Infection Cancer
    Ivermectin (Standard) is the analytical standard of Ivermectin. This product is intended for research and analytical applications. Ivermectin (MK-933) is a broad-spectrum anti-parasite agent. Ivermectin (MK-933) is a specific inhibitor of Impα/β1-mediated nuclear import and has potent antiviral activity towards both HIV-1 and dengue virus. It is a positive allosteric effector of P2X4 and the α7 neuronal nicotinic acetylcholine receptor (nAChRs). Ivermectin also inhibits bovine herpesvirus1 (BoHV-1) replication and inhibits BoHV-1 DNA polymerase nuclear import . Ivermectin is a candidate therapeutic against SARS-CoV-2/COVID-19 .
    Ivermectin (Standard)

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

 

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

 

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: