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PKR1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	G Protein-coupled Receptor Kinase (GRK) (1) Pyruvate Kinase (1)
By Research Areas:	Cancer (2) Inflammation/Immunology (1) Neurological Disease (1)

3

Inhibitors & Agonists

1

Recombinant Proteins

1

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

PKRA83 PKRA7	Others	Inflammation/Immunology Cancer
PKRA83 (PKRA7) is a potent prokineticin (PK2) antagonist, which can compete for the binding of PK2 to its receptors PKR1 and PKR2. PKRA83 potently inhibits PK2 receptors, with IC₅₀ values of 5.0 nM and 8.2 nM for PKR1 and PKR2, respectively. PKRA83 has anticancer, anti-arthritis and anti-angiogenic activities. PKRA83 can penetrate the blood-brain barrier ^[1] .

TEPP-46 35+ Cited Publications ML-265	Pyruvate Kinase	Cancer
TEPP-46 (ML-265) is a potent and selective pyruvate kinase M2 (PKM2) activator with an AC₅₀ of 92 nM, showing little or no effect on PKM1, PKL and PKR .

PKR1 antagonist 1	G Protein-coupled Receptor Kinase (GRK)	Neurological Disease
PKR1 antagonist 1 (PC1) is a potent *PKR1* antagonist. PKR1 antagonist 1 reduces hyperalgesia and allodynia in SNI mice ^[1].

Cat. No.	Compare	Product Name	Species	Source

	PRKAR1A Protein, Mouse (sf9, His) cAMP-dependent protein kinase type I-alpha regulatory subunit; Tissue-specific extinguisher 1; TSE1; PKR1; PRKAR1	Mouse	Sf9 insect cells
	PRKAR1A protein is a regulatory subunit of cAMP-dependent protein kinase that mediates cellular responses to cAMP signaling.The inactive holoenzyme has two regulatory chains and two catalytic chains.PRKAR1A Protein, Mouse (sf9, His) is the recombinant mouse-derived PRKAR1A protein, expressed by Sf9 insect cells , with C-His labeled tag.

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	PKA RI alpha Antibody (YA1751) PRKAR1A; PKR1; PRKAR1; TSE1; cAMP-dependent protein kinase type I-alpha regulatory subunit; Tissue-specific extinguisher 1; TSE1	WB	Human, Rat
	PKA RI alpha Antibody (YA1751) is a non-conjugated IgG antibody, targeting PKA RI alpha, with a predicted molecular weight of 43 kDa (observed band size: 43 kDa). PKA RI alpha Antibody (YA1751) can be used for WB experiment in human, rat background.

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