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PLX 5622

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-114153
    PLX5622
    45+ Cited Publications

    		 c-Fms Neurological Disease
    PLX5622 is a highly selective brain penetrant and orally active CSF1R inhibitor (IC50=0.016 μM; Ki=5.9 nM). PLX5622 allows for extended and specific microglial cells elimination, preceding and during pathology development. PLX5622 demonstrates desirable PK properties in varies animals .
    PLX5622
  • HY-114153A
    PLX5622 hemifumarate
    45+ Cited Publications

    		 c-Fms Neurological Disease
    PLX5622 hemifumarate is a highly selective brain penetrant and orally active CSF1R inhibitor (IC50=0.016 μM; Ki=5.9 nM). PLX5622 hemifumarate allows for extended and specific microglial elimination, preceding and during pathology development. PLX5622 hemifumarate demonstrates desirable PK properties in varies animals .
    PLX5622 hemifumarate

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