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PRT3789

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-172735
    PRT3789

    		PROTACs Epigenetic Reader Domain Cancer
    PRT3789 is a potent, selective and VHL-based SMARCA2 PROTAC degrader. PRT3789 is more selective for SMARCA2 than SMARCA4. PRT3789 has robust inhibition of cell proliferation of SMARCA4-deleted non-small cell lung cancer (NSCLC) cells in vitro and in vivo, but not SMARCA4 wild type cancer cells (Pink: Target protein ligand (HY-44824); Black: linker (HY-79552); Blue: E3 ligase ligand (HY-168143)) . (粉色：靶蛋白配体 (HY-44824)；黑色：连接子 (HY-79552)；蓝色：E3 连接酶配体 (HY-112078))
    PRT3789

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