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Results for "

Pirfenidone

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0673
    Pirfenidone
    45+ Cited Publications

    AMR69

    		 TGF-beta/Smad CCR Inflammation/Immunology Cancer
    Pirfenidone (AMR69) is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities .
    Pirfenidone
  • HY-B0673S
    Pirfenidone-d5

    AMR69-d5

    		 TGF-beta/Smad CCR Inflammation/Immunology Cancer
    Pirfenidone-d5 is a deuterium labeled Pirfenidone. Pirfenidone is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities[1][2][3].
    Pirfenidone-d5
  • HY-B0673R
    Pirfenidone (Standard)

    		TGF-beta/Smad CCR Inflammation/Immunology Cancer
    Pirfenidone (Standard) is the analytical standard of Pirfenidone. This product is intended for research and analytical applications. Pirfenidone (AMR69) is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities .
    Pirfenidone (Standard)
  • HY-160851
    GDC-3280

    AK3287; AKEX0011

    		 ASK1 p38 MAPK Inflammation/Immunology
    GDC-3280 (AK3287; AKEX0011) is an orally active compound based on Pirfenidone (HY-B0673)'s phenyl pyridone scaffold. GDC-3280 alleviates the inflammatory and fibrotic reaction of silicosis by inhibiting the ASK1-p38 MAPK pathway and regulating macrophage polarization. GDC-3280 exhibits anti-inflammatory and anti-fibrotic effects .
    GDC-3280
  • HY-B0673S1
    Deupirfenidone

    LYT-100; AMR69-d3

    		 Isotope-Labeled Compounds Others
    Deupirfenidone-d3-d3 is the deuterium labeled Pirfenidone (HY-B0673)[1].
    Deupirfenidone

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