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SARS-CoV-2-IN-109

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-170767
    SARS-CoV-2-IN-109

    		SARS-CoV Infection
    SARS-CoV-2-IN-109 (compound 50) is an inhibitor targeting SARS-CoV with in vivo anti-infection activity. SARS-CoV-2-IN-109 targets the interaction between the SARS-CoV-2 Spike receptor-binding domain (RBD) and the human receptor angiotensin-converting enzyme 2 (ACE2) (EC50=26.5 μM), blocking the entry of SARS-CoV-2 into VeroE6 cells (EC50=17.0 μM). The CC50 of SARS-CoV-2-IN-109 for VeroE6 cells is >100 μM .
    SARS-CoV-2-IN-109

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