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Results for "

SETD2

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Peptides

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-136328
    EZM0414 TFA
    4 Publications Verification

    SETD2-IN-1 TFA

    		 Histone Methyltransferase Cancer
    EZM0414 TFA is a potent, selective and orally active inhibitor of SETD2 which is a human histone methyltransferase. EZM0414 TFA has anti-proliferative effects .
    EZM0414 TFA
  • HY-144858
    EZM0414
    4 Publications Verification

    		 Histone Methyltransferase Cancer
    EZM0414 is a potent, selective, orally bioavailable inhibitor of SETD2 (IC50=18 nM in SETD2 biochemical assay; IC50=34 nM in cellular assay). EZM0414 can be used for the research of relapsed or refractory multiple myeloma and diffuse large B-cell lymphoma .
    EZM0414
  • HY-139626
    EPZ-719

    		Histone Methyltransferase Cancer
    EPZ-719 is a selective, orally effective SETD2 inhibitor with an IC50 value of 0.005 μM. EPZ-719 has anticancer activity .
    EPZ-719
  • HY-RS12742
    SETD2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    SETD2 Human Pre-designed siRNA Set A contains three designed siRNAs for SETD2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SETD2 Human Pre-designed siRNA Set A
    SETD2 Human Pre-designed siRNA Set A
  • HY-P10463
    ssK36

    		Histone Methyltransferase Cancer
    ssK36 is a supersubstrate peptide of the histone methyltransferase (SET) domain protein 2 (SETD2), and ssK36 is designed for the SETD2 protein, a specific PKMT. It is responsible in human cells for adding methyl groups to the 36th lysine residue of histone H3 (H3K36) to form H3K36me3. ssK36 can be methylated by SETD2 at a rate more than 100 times faster than the natural substrate H3K36. ssK36 can be used to study the catalytic mechanism of PKMTs, especially substrate specificity and catalytic efficiency .
    ssK36
  • HY-124699
    MMSET-IN-1

    		Others Cancer
    MMSET-IN-1 is a multiple myeloma SET domain (MMSET, aka NSD2/WHSC1) inhibitor against SETD2 and MMSET with IC50s of 0.49 and 3.3 μM, respectively. MMSET-IN-1 has a Kd of 1.6 μM for MMSET .
    MMSET-IN-1

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