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SM-5887

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0067
    Amrubicin

    SM-5887

    		 Topoisomerase Bacterial Cancer
    Amrubicin (SM-5887) is a DNA topoisomerase II inhibitor, used for the research of cancer.
    Amrubicin
  • HY-B0067A
    Amrubicin hydrochloride

    SM-5887 hydrochloride

    		 Topoisomerase Bacterial Cancer
    Amrubicin (SM-5887) hydrochloride is a DNA topoisomerase II inhibitor, used for the research of cancer.
    Amrubicin hydrochloride
  • HY-B0067B
    (R)-Amrubicin

    (R)-SM-5887

    		 Others Cancer
    (R)-Amrubicin ((R)-SM-5887) is an anthracycline that effectively treats lung cancer by intercalating into DNA and inhibiting topoisomerase II activity, which consequently hampers DNA replication as well as RNA and protein synthesis, leading to cell growth inhibition and apoptosis. This compound exhibits superior anti-tumor efficacy compared to traditional anthracycline drugs while lacking the cumulative cardiac toxicity typically associated with this drug class.
    (R)-Amrubicin

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