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Results for "

SRPK1

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-114653
    SRPIN803

    		Casein Kinase SRPK Cancer
    SRPIN803 is a potent CK2 and SRPK1 dual inhibitor, with IC50s of 203 nM and 2.4 μM, respectively. SRPIN803 exhibits antiangiogenic activity. SRPIN803 can be used for the research of age-related macular degeneration [1] .
    SRPIN803
  • HY-148518
    MSC-1186

    		SRPK Cancer
    MSC-1186 is a highly selective pan-SRPK inhibitor. MSC-1186 has activity for SRPK1, SRPK2 and SRPK3 with IC50 values of 2.7 nM, 81 nM and 0.6 nM, respectively. MSC-1186 can be used for the research of cancer [1].
    MSC-1186
  • HY-13949
    SRPIN340
    Maximum Cited Publications
    10 Publications Verification

    SRPK inhibitor

    		 SRPK Virus Protease Cancer
    SRPIN340 is an ATP-competitive serine-arginine-rich protein kinase (SRPK) inhibitor, with a Ki of 0.89 μM for SRPK1.
    SRPIN340
  • HY-116856
    SRPKIN-1
    4 Publications Verification

    		 SRPK Cardiovascular Disease Cancer
    SRPKIN-1 is a covalent and irreversible SRPK1/2 inhibitor with IC50s of 35.6 and 98 nM, respectively. Anti-angiogenesis effect [1].
    SRPKIN-1
  • HY-132126
    SPHINX

    		SRPK Others
    SPHINX is a selective SRPK1 inhibitor with an IC50 value of 0.58 μM. SPHINX effectively reduces Choroidal Neovascularization (CNV) in vivo. SPHINX can be used for the research of (age-related macular degenaration) AMD [1].
    SPHINX
  • HY-117661
    SPHINX31
    5+ Cited Publications

    		 SRPK VEGFR Cardiovascular Disease Cancer
    SPHINX31 is a potent and selective SRPK1 inhibitor, with an IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1). SPHINX31 also decreases the mRNA expression of pro-angiogenic VEGF-A165a isoform. SPHINX31 can be used to research neovascular eye disease [1] .
    SPHINX31
  • HY-RS13777
    SRPK1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    SRPK1 Human Pre-designed siRNA Set A contains three designed siRNAs for SRPK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    SRPK1 Human Pre-designed siRNA Set A
    SRPK1 Human Pre-designed siRNA Set A
  • HY-160586
    Srpk1-IN-1

    		SRPK Others
    Srpk1-IN-1 (compound 12) is a potent inhibitor of SRPK1, with IC50 of 0.3 nM [1].
    Srpk1-IN-1
  • HY-160587
    Antiangiogenic agent 5

    		SRPK Cardiovascular Disease
    Antiangiogenic agent 5 (compound 17) has anti-angiogenic activity. Antiangiogenic agent 5 show inhibition to SRPK1, with IC50 of 1.3 nM [1].
    Antiangiogenic agent 5
  • HY-113831
    CLK1/2-IN-3

    		CDK SRPK Cancer
    LK1/2-IN-3 (compound 3) is a potent and selective CLK1 and CLK2 inhibitor with IC50 values of 1.1, 2.1, 130, 260, 260 nM for CLK1, CLK2, SRPK1, SRPK2, SRPK3, respectively. CLK1/2-IN-3 shows anti-proliferative activity. CLK1/2-IN-3 reduces the levels of endogenous phosphorylated SR proteins and increases the expression of S6K mRNAs [1].
    CLK1/2-IN-3

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