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Results for "

SSB

" in MedChemExpress (MCE) Product Catalog:

By Targets:	DNA/RNA Synthesis (2) PARP (5) PPAR (1) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (5) Neurological Disease (1)
Oligonucleotides:	Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-137457

Venadaparib IDX-1197	PARP	Cancer
Venadaparib (IDX-1197) is a potent, selective and orally active PARP inhibitor with IC₅₀s of 1.4 nM and 1.0 nM for PARP1 and PARP2, respectively. Venadaparib does not sensitive to PARP-5. Venadaparib prevents the repair of DNA single-strand breaks (SSB) and can be used for solid tumors research .

HY-145804

AZD-9574 1 Publications Verification	PPAR	Neurological Disease
AZD-9574 is a potent and brain penetrant PARP1 inhibitor and shows >8000-fold selectivity for PARP1 compared to PARP2/3/5a/6. AZD-9574 acts by selectively inhibiting and trapping PARP1 at the sites of SSBs. AZD-9574 is an anti-cancer agent and can be used for HRD ⁺ breast cancer and advanced solid malignancies research .

HY-10617

Rucaparib phosphate Maximum Cited Publications 38 Publications Verification AG-014699 phosphate; PF-01367338 phosphate	PARP	Cancer
Rucaparib (AG014699) phosphate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a K_i of 1.4 nM for PARP1. Rucaparib phosphate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib phosphate has the potential for castration-resistant prostate cancer (CRPC) research .

HY-10617A

Rucaparib Maximum Cited Publications 38 Publications Verification AG014699; PF-01367338	PARP	Cancer
Rucaparib (AG014699) is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a K_i of 1.4 nM for PARP1. Rucaparib is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib has the potential for castration-resistant prostate cancer (CRPC) research .

HY-102003

Rucaparib monocamsylate Maximum Cited Publications 38 Publications Verification AG014699 monocamsylate; PF-01367338 monocamsylate	PARP	Cancer
Rucaparib (AG014699) monocamsylate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a K_i of 1.4 nM for PARP1. Rucaparib monocamsylate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib monocamsylate has the potential for castration-resistant prostate cancer (CRPC) research .

HY-RS13804

SSB Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SSB Human Pre-designed siRNA Set A contains three designed siRNAs for SSB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SSB Human Pre-designed siRNA Set A SSB Human Pre-designed siRNA Set A

HY-W159870

N-Nitrosodibenzylamine	DNA/RNA Synthesis	Others
N-Nitrosodibenzylamine is a potent and orally activity DNA damage inducer. N-Nitrosodibenzylamine induces DNA single-strand breaks (SSBs) .

HY-W159870R

N-Nitrosodibenzylamine (Standard)	DNA/RNA Synthesis	Others
N-Nitrosodibenzylamine (Standard) is the analytical standard of N-Nitrosodibenzylamine. This product is intended for research and analytical applications. N-Nitrosodibenzylamine is a potent and orally activity DNA damage inducer. N-Nitrosodibenzylamine induces DNA single-strand breaks (SSBs) .

HY-102003A

Rucaparib camsylate AG014699 camsylate; PF-01367338 camsylate	PARP	Cancer
Rucaparib (AG014699) camsylate is an orally active, potent inhibitor of PARP proteins (PARP-1, PARP-2 and PARP-3) with a K_i of 1.4 nM for PARP1. Rucaparib camsylate is a modest hexose-6-phosphate dehydrogenase (H6PD) inhibitor. Rucaparib camsylate has the potential for castration-resistant prostate cancer (CRPC) research .

Species:	Human (4)
Tag:	His (3) Tag Free (1)
Source:	Sf9 insect cells (1) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

HY-P73630A

	SSB Protein, Human Lupus La protein; Sjoegren syndrome type B antigen; SS-B	Human	E. coli
	The SSB protein critically binds to the 3' poly(U) terminus of RNA polymerase III transcripts, preventing exonuclease digestion and aiding in correct folding. In coxsackievirus B3 infection, SSB binds to the viral internal ribosome entry site (IRES) and enhances IRES-mediated translation. SSB Protein, Human is the recombinant human-derived SSB protein, expressed by E. coli , with tag free. The total length of SSB Protein, Human is 408 a.a., with molecular weight of ~50 kDa.

HY-P73630

	SSB Protein, Human (His) Lupus La protein; Sjoegren syndrome type B antigen; SS-B	Human	E. coli
	SSB Protein crucially binds to the 3' poly(U) terminus of RNA polymerase III transcripts, safeguarding against exonuclease digestion and aiding proper folding. In Coxsackievirus B3 infection, SSB binds to the viral internal ribosome entry site (IRES), enhancing IRES-mediated translation. Interactions with DDX15 and potential interactions with RUFY1 underscore SSB's involvement in diverse cellular processes, emphasizing its multifunctional nature. SSB Protein, Human (His) is the recombinant human-derived SSB protein, expressed by E. coli, with N-His labeled tag. The total length of SSB Protein, Human (His) is 408 a.a., with molecular weight of ~47.8 kDa.

HY-P73629

	SSB Protein, Human (sf9, His) Lupus La protein; Sjoegren syndrome type B antigen; SS-B	Human	Sf9 insect cells
	SSB Protein crucially binds to the 3' poly(U) terminus of RNA polymerase III transcripts, safeguarding against exonuclease digestion and aiding proper folding. In Coxsackievirus B3 infection, SSB binds to the viral internal ribosome entry site (IRES), enhancing IRES-mediated translation. Interactions with DDX15 and potential interactions with RUFY1 underscore SSB's involvement in diverse cellular processes, emphasizing its multifunctional nature. SSB Protein, Human (sf9, His) is the recombinant human-derived SSB protein, expressed by Sf9 insect cells, with N-His labeled tag. The total length of SSB Protein, Human (sf9, His) is 408 a.a., with molecular weight of ~49.2 kDa.

HY-P703378

	SPSB4 Protein, Human (His) SSB4	Human	E. coli
	SPSB4 Protein, Human (His) is the recombinant human-derived SPSB4, expressed by E. coli , with His labeled tag. ,

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HY-P80901

	SSB Antibody (YA668) La; LARP3; La/SSB	WB	Human
	SSB Antibody (YA668) is a non-conjugated and Mouse origined monoclonal antibody about 47 kDa, targeting to SSB (4B10). It can be used for WB assays with tag free, in the background of Human.

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SSB Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
SSB Human Pre-designed siRNA Set A contains three designed siRNAs for SSB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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