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Results for "

ST-246

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-14805
    Tecovirimat

    ST-246

    		 Arenavirus Orthopoxvirus Infection Inflammation/Immunology
    Tecovirimat (ST-246) is an orally bioavailable and selective compound against orthopoxviruses [including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), smallpox and variola viruses]. Tecovirimat is evaluated against vaccinia, cowpox virus, ectromelia virus with EC50 values of 0.01 μM, 0.48 μM and 0.05 μM, respectively. Tecovirimat targets the orthopoxvirus protein VP37 which is necessary for membrane envelopment of intracellular mature virus particles to form enveloped virus. Tecovirimat exerts antiviral activity on the target of the cowpox virus V061 gene, which is homologous to vaccinia virus F13L, encoding a major envelope protein (p37) required for production of extracellular virus .
    Tecovirimat
  • HY-14805A
    Tecovirimat monohydrate

    ST-246 monohydrate

    		 Orthopoxvirus Arenavirus Infection
    Tecovirimat (ST-246) monohydrate is the monohydrate form of Tecovirimat (HY-14805). Tecovirimat monohydrate is an orally bioavailable and selective compound against orthopoxviruses [including vaccinia, monkeypox, camelpox, cowpox, ectromelia (mousepox), smallpox and variola viruses]. Tecovirimat monohydrate is evaluated against vaccinia, cowpox virus, ectromelia virus with EC50 values of 0.01 μM, 0.48 μM and 0.05 μM, respectively. Tecovirimat monohydrate targets the orthopoxvirus protein VP37 which is necessary for membrane envelopment of intracellular mature virus particles to form enveloped virus. Tecovirimat monohydrate exerts antiviral activity on the target of the cowpox virus V061 gene, which is homologous to vaccinia virus F13L, encoding a major envelope protein (p37) required for production of extracellular virus. Tecovirimat monohydrate could be used in the study for orthopoxvirus-induced diseases .
    Tecovirimat monohydrate
  • HY-14805S
    Tecovirimat-d4

    ST-246-d4

    		 Isotope-Labeled Compounds Others
    Tecovirimat-d4 is a deuterium-labelled Tecovirimat. Tecovirimat is an orally active viral inhibitor with high activity against viruses of the genus Orthopoxvirus, including smallpox, cowpox and monkeypox viruses[1].
    Tecovirimat-d4
  • HY-14805R
    Tecovirimat (Standard)

    		Arenavirus Orthopoxvirus Infection
    Tecovirimat (Standard) is the analytical standard of Tecovirimat. This product is intended for research and analytical applications. Tecovirimat(ST-246) is an orally bioavailable antipoxvirus compound; potent and selective active against multiple orthopoxviruses with EC50 about 10 nM. Tecovirimat could be used in the study for orthopoxvirus-induced diseases.
    Tecovirimat (Standard)

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