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Results for "

SYN117

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-13289A
    Nepicastat hydrochloride
    3 Publications Verification

    SYN-117 hydrochloride; RS-25560-197 hydrochloride

    		 Dopamine β-hydroxylase Cardiovascular Disease
    Nepicastat hydrochloride (SYN-117 hydrochloride) is a selective, potent, and orally active inhibitor of dopamine-beta-hydroxylase. Nepicastat hydrochloride produces concentration-dependent inhibition of bovine (IC50=8.5 nM) and human (IC50=9 nM) dopamine-beta-hydroxylase. Nepicastat hydrochloride can cross the blood-brain barrier (BBB) .
    Nepicastat hydrochloride
  • HY-13289
    Nepicastat

    SYN117; RS-25560-197

    		 Dopamine β-hydroxylase Cardiovascular Disease
    Nepicastat (SYN117) is a selective, potent, and orally active inhibitor of dopamine-beta-hydroxylase. Nepicastat (SYN117) produces concentration-dependent inhibition of bovine (IC50=8.5 nM) and human (IC50=9 nM) dopamine-beta-hydroxylase. Nepicastat (SYN117) can cross the blood-brain barrier (BBB) .
    Nepicastat
  • HY-13289B
    (R)-Nepicastat hydrochloride

    (R)-SYN117 hydrochloride; (R)-RS-25560-197 hydrochloride; RS-25560-198 hydrochloride

    		 Dopamine β-hydroxylase Cardiovascular Disease
    (R)-Nepicastat hydrochloride is the isomer of Nepicastat (HY-13289). Nepicastat (SYN117) is a selective，potent，and orally active inhibitor of dopamine-beta-hydroxylase. Nepicastat (SYN117) produces concentration-dependent inhibition of bovine (IC50=8.5 nM) and human (IC50=9 nM) dopamine-beta-hydroxylase. Nepicastat (SYN117) can cross the blood-brain barrier (BBB) .
    (R)-Nepicastat hydrochloride

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