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Scutellaria baicalensis

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (2) Bacterial (2) Enterovirus (2) HIV (2) Prolyl Endopeptidase (PREP) (2) STAT (2) TNF Receptor (1)
By Research Areas:	Cancer (3) Infection (6) Inflammation/Immunology (3) Neurological Disease (2)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N2562

Norwogonin 5,7,8-Trihydroxyflavone	Enterovirus	Infection
Norwogonin, isolated from Scutellaria baicalensis Georgi, possesses antiviral activity against Enterovirus 71 (EV71) with an IC₅₀ of 31.83 μg/ml

HY-122941

Viscidulin II	Others	Inflammation/Immunology
Viscidulin II (FL6) is a flavone. Viscidulin II can be isolated from the root of Scutellaria baicalensis. Viscidulin II significantly suppresses P. acnes-induced IL-8 and IL-1β production in THP-1 cells .

HY-N2376

Chrysin-7-O-glucuronide 1 Publications Verification	Others	Others
Chrysin-7-O-glucuronide is a flavonoid extracted from Scutellaria baicalensis, with antioxidant activity .

HY-N12793

5,6-Dihydroxy-8-methoxyflavone-7-O-glucuronide	Others	Others
5,6-Dihydroxy-8-methoxyflavone-7-O-glucuronide (Compound 8) is a flavonoid glycoside and can be isolated from Scutellaria baicalensis .

HY-N10799

Oroxylin A 7-O-β-D-glucuronide methyl ester	Others	Others
Oroxylin A 7-O-β-D-glucuronide methyl ester is a nature product that could be isolated form the roots of Scutellaria baicalensis Georgi .

HY-N1085

Viscidulin I	Others	Others
Viscidulin I is found in Scutellaria baicalensis Georgi .

HY-N1676

2′,3,5,6′,7-Pentahydroxyflavanone 3,5,7,2',6'-Pentahydroxyflavanone	Others	Others
2′,3,5,6′,7-Pentahydroxyflavanone (compound 4) is a flavonoid compound isolated from Scutellaria baicalensis roots .

HY-N10043

5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone	Others	Others
5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone is a Flavonoids product that can be isolated from the roots of Scutellaria baicalensis Georgi .

HY-N8595

2(S)-5,7,2'-Trihydroxy-8-methoxyflavanone	Others	Others
2(S)-5,7,2'-Trihydroxy-8-methoxyflavanone is a Flavonoids product that can be isolated from the roots of Scutellaria baicalensis Georgi .

HY-N11488

5,7,8-Trihydroxy-6-methoxy flavone-7-O-glucuronideb	Others	Others
5,7,8-Trihydroxy-6-methoxy flavone-7-O-glucuronideb is a natural product that can be isolated from Scutellaria baicalensis Georgi .

HY-N2481

Oroxylin A-7-O-glucuronide Oroxyloside; Oroxylin A-7-O-β-D-glucuronide	Prolyl Endopeptidase (PREP)	Neurological Disease
Oroxylin A-7-O-glucuronide (Oroxyloside; Oroxylin A-7-O-β-D-glucuronide) is a flavonoid glucuronide isolated from the dried root of Scutellaria baicalensis, with prolyl oligopeptidase (POP) inhibitory activity .

HY-N6624

Skullcapflavone II	Bacterial	Inflammation/Immunology
Skullcapflavone II, a flavonoid derived from Scutellaria baicalensis, has anti-inflammatory, anti-microbial activities. Skullcapflavone II regulates osteoclast differentiation, survival, and function. Skullcapflavone II exerts potent antimicrobial activity against M. aurum and M. bovis BCG .

HY-N2376R

Chrysin-7-O-glucuronide (Standard)	Others	Others
Chrysin-7-O-glucuronide (Standard) is the analytical standard of Chrysin-7-O-glucuronide. This product is intended for research and analytical applications. Chrysin-7-O-glucuronide is a flavonoid extracted from Scutellaria baicalensis, with antioxidant activity .

HY-N1672

5,7,2′,6′-Tetrahydroxyflavanone	Others	Infection
5,7,2 ',6 '-Tetrahydroxyflavanone is an extract isolated from Scutellaria baicalensis. 5,7,2 ',6 '-Tetrahydroxyflavanone has significant antibacterial activity against gram-positive bacteria. 5,7,2 ',6 '-Tetrahydroxyflavanone can be used to study the treatment of inflammatory diseases .

HY-N7681

Taxifolin 7-O-β-D-glucoside 1 Publications Verification Taxifolin 7-O-glucoside	Others	Others
Taxifolin 7-O-β-D-glucoside (Taxifolin 7-O-glucoside) is one of the main metabolites at the seed germination stage in Scutellaria baicalensis. Taxifolin 7-O-β-D-glucoside, a flavonoid, mainly exists in the episperm and participates in defending against pathogens and UV-damage .

HY-N1671

2',5,6',7-Tetraacetoxyflavanone	Others	Infection
2',5,6',7-Tetraacetoxyflavanone is an extract isolated from Scutellaria baicalensis. 2',5,6',7-Tetraacetoxyflavanone shows significant antibacterial activity against gram-positive bacteria. 2',5,6',7-Tetraacetoxyflavanone can be used to study the treatment of inflammatory diseases .

HY-N2036

Mosloflavone	TNF Receptor Enterovirus Bacterial	Infection
Mosloflavone is a flavonoid isolated from Scutellaria baicalensis Georgi with ?anti-EV71 activity. Mosloflavone? inhibits VP2 virus replication and protein expression during the initial stage of virus infection and inhibits viral VP2 capsid protein synthesis. Mosloflavone is a promising biocide and inhibits P. aeruginosa virulence and biofilm formation.

HY-N2481R

Oroxylin A-7-O-glucuronide (Standard)	Prolyl Endopeptidase (PREP)	Neurological Disease
Oroxylin A-7-O-glucuronide (Standard) is the analytical standard of Oroxylin A-7-O-glucuronide. This product is intended for research and analytical applications. Oroxylin A-7-O-glucuronide (Oroxyloside; Oroxylin A-7-O-β-D-glucuronide) is a flavonoid glucuronide isolated from the dried root of Scutellaria baicalensis, with prolyl oligopeptidase (POP) inhibitory activity .

HY-N0751

Scutellarin Maximum Cited Publications 9 Publications Verification	STAT Akt HIV	Infection Cancer
Scutellarin, an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts. Scutellarin is active against HIV-1IIIB, HIV-1(74V) and HIV-1KM018 with EC₅₀s of 26 μM, 253 μM and 136 μM, respectively.

HY-N0751R

Scutellarin (Standard)	STAT Akt HIV	Infection Cancer
Scutellarin (Standard) is the analytical standard of Scutellarin. This product is intended for research and analytical applications. Scutellarin, an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts. Scutellarin is active against HIV-1IIIB, HIV-1(74V) and HIV-1KM018 with EC₅₀s of 26 μM, 253 μM and 136 μM, respectively.

HY-N8788

Baicalein 7-O-β-D-ethylglucuronide	Others	Inflammation/Immunology Cancer
Baicalein 7-O-β-D-ethylglucuronide is a natural flavone glycoside that can be extracted from Scutellaria baicalensis Georgi. Baicalein 7-O-β-D-ethylglucuronide has antioxidant activity. Baicalein 7-O-β-D-ethylglucuronide inhibits FeSO₄-Cys-induced lipid peroxidation of liver homogenate. Baicalein 7-O-β-D-ethylglucuronide also shows strong cytoprotective effect on H₂O₂-induced oxidative damage of human umbilical vein endothelial cells .

Norwogonin 5,7,8-Trihydroxyflavone	Infection Flavonoids Classification of Application Fields Flavones Labiatae Source classification Phenols Polyphenols Plants Disease Research Fields Medicago truncatula Gaertn.	Enterovirus
Norwogonin, isolated from Scutellaria baicalensis Georgi, possesses antiviral activity against Enterovirus 71 (EV71) with an IC₅₀ of 31.83 μg/ml

Viscidulin II	Structural Classification Flavonoids Flavones Labiatae Source classification Plants Medicago truncatula Gaertn.	Others
Viscidulin II (FL6) is a flavone. Viscidulin II can be isolated from the root of Scutellaria baicalensis. Viscidulin II significantly suppresses P. acnes-induced IL-8 and IL-1β production in THP-1 cells .

Chrysin-7-O-glucuronide 1 Publications Verification	Structural Classification Classification of Application Fields Flavones Source classification Plants Oroxylum indicum (Linn.) Bentham ex Kurz Monophenols Flavonoids Labiatae Other Diseases Phenols Bignoniaceae Medicago truncatula Gaertn. Disease Research Fields	Others
Chrysin-7-O-glucuronide is a flavonoid extracted from Scutellaria baicalensis, with antioxidant activity .

Oroxylin A-7-O-glucuronide Oroxyloside; Oroxylin A-7-O-β-D-glucuronide	Structural Classification Monophenols Flavonoids Neurological Disease Classification of Application Fields Flavones Labiatae Source classification Phenols Plants Medicago truncatula Gaertn. Disease Research Fields	Prolyl Endopeptidase (PREP)
Oroxylin A-7-O-glucuronide (Oroxyloside; Oroxylin A-7-O-β-D-glucuronide) is a flavonoid glucuronide isolated from the dried root of Scutellaria baicalensis, with prolyl oligopeptidase (POP) inhibitory activity .

5,6-Dihydroxy-8-methoxyflavone-7-O-glucuronide	Structural Classification Flavonoids Flavones Labiatae Source classification Plants Medicago truncatula Gaertn.	Others
5,6-Dihydroxy-8-methoxyflavone-7-O-glucuronide (Compound 8) is a flavonoid glycoside and can be isolated from Scutellaria baicalensis .

Oroxylin A 7-O-β-D-glucuronide methyl ester	Structural Classification Flavonoids Flavones Labiatae Source classification Plants Medicago truncatula Gaertn.	Others
Oroxylin A 7-O-β-D-glucuronide methyl ester is a nature product that could be isolated form the roots of Scutellaria baicalensis Georgi .

Viscidulin I	Flavonols Flavonoids Artemisia tridentata Nutt. Classification of Application Fields Labiatae Source classification Other Diseases Phenols Polyphenols Plants Disease Research Fields	Others
Viscidulin I is found in Scutellaria baicalensis Georgi .

5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone	Structural Classification Flavonoids Flavones Labiatae Source classification Plants Medicago truncatula Gaertn.	Others
5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone is a Flavonoids product that can be isolated from the roots of Scutellaria baicalensis Georgi .

2(S)-5,7,2'-Trihydroxy-8-methoxyflavanone	Structural Classification Flavonoids Flavones Labiatae Source classification Plants Medicago truncatula Gaertn.	Others
2(S)-5,7,2'-Trihydroxy-8-methoxyflavanone is a Flavonoids product that can be isolated from the roots of Scutellaria baicalensis Georgi .

5,7,8-Trihydroxy-6-methoxy flavone-7-O-glucuronideb	Structural Classification Flavonoids Flavones Labiatae Source classification Plants Medicago truncatula Gaertn.	Others
5,7,8-Trihydroxy-6-methoxy flavone-7-O-glucuronideb is a natural product that can be isolated from Scutellaria baicalensis Georgi .

Skullcapflavone II	Flavonoids other families Classification of Application Fields Flavones Source classification Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology	Bacterial
Skullcapflavone II, a flavonoid derived from Scutellaria baicalensis, has anti-inflammatory, anti-microbial activities. Skullcapflavone II regulates osteoclast differentiation, survival, and function. Skullcapflavone II exerts potent antimicrobial activity against M. aurum and M. bovis BCG .

Chrysin-7-O-glucuronide (Standard)	Structural Classification Monophenols Flavonoids Flavones Labiatae Source classification Phenols Bignoniaceae Plants Oroxylum indicum (Linn.) Bentham ex Kurz Medicago truncatula Gaertn.	Others
Chrysin-7-O-glucuronide (Standard) is the analytical standard of Chrysin-7-O-glucuronide. This product is intended for research and analytical applications. Chrysin-7-O-glucuronide is a flavonoid extracted from Scutellaria baicalensis, with antioxidant activity .

5,7,2′,6′-Tetrahydroxyflavanone	Structural Classification Flavonoids Labiatae Flavonones Source classification Plants Medicago truncatula Gaertn.	Others
5,7,2 ',6 '-Tetrahydroxyflavanone is an extract isolated from Scutellaria baicalensis. 5,7,2 ',6 '-Tetrahydroxyflavanone has significant antibacterial activity against gram-positive bacteria. 5,7,2 ',6 '-Tetrahydroxyflavanone can be used to study the treatment of inflammatory diseases .

Taxifolin 7-O-β-D-glucoside 1 Publications Verification Taxifolin 7-O-glucoside	Flavanonols Flavonoids Classification of Application Fields Cercis chinensis Bunge Source classification Other Diseases Phenols Polyphenols Plants Compositae Disease Research Fields	Others
Taxifolin 7-O-β-D-glucoside (Taxifolin 7-O-glucoside) is one of the main metabolites at the seed germination stage in Scutellaria baicalensis. Taxifolin 7-O-β-D-glucoside, a flavonoid, mainly exists in the episperm and participates in defending against pathogens and UV-damage .

2',5,6',7-Tetraacetoxyflavanone	Structural Classification Flavonoids Labiatae Flavonones Source classification Plants Medicago truncatula Gaertn.	Others
2',5,6',7-Tetraacetoxyflavanone is an extract isolated from Scutellaria baicalensis. 2',5,6',7-Tetraacetoxyflavanone shows significant antibacterial activity against gram-positive bacteria. 2',5,6',7-Tetraacetoxyflavanone can be used to study the treatment of inflammatory diseases .

Mosloflavone	Infection Structural Classification Monophenols Flavonoids Classification of Application Fields Flavones Labiatae Source classification Phenols Plants Medicago truncatula Gaertn. Disease Research Fields	TNF Receptor Enterovirus Bacterial
Mosloflavone is a flavonoid isolated from Scutellaria baicalensis Georgi with ?anti-EV71 activity. Mosloflavone? inhibits VP2 virus replication and protein expression during the initial stage of virus infection and inhibits viral VP2 capsid protein synthesis. Mosloflavone is a promising biocide and inhibits P. aeruginosa virulence and biofilm formation.

Oroxylin A-7-O-glucuronide (Standard)	Structural Classification Monophenols Flavonoids Flavones Labiatae Source classification Phenols Plants Medicago truncatula Gaertn.	Prolyl Endopeptidase (PREP)
Oroxylin A-7-O-glucuronide (Standard) is the analytical standard of Oroxylin A-7-O-glucuronide. This product is intended for research and analytical applications. Oroxylin A-7-O-glucuronide (Oroxyloside; Oroxylin A-7-O-β-D-glucuronide) is a flavonoid glucuronide isolated from the dried root of Scutellaria baicalensis, with prolyl oligopeptidase (POP) inhibitory activity .

Scutellarin Maximum Cited Publications 9 Publications Verification	Infection Structural Classification Flavonoids Classification of Application Fields Flavones Labiatae Source classification Phenols Polyphenols Plants Medicago truncatula Gaertn. Disease Research Fields	STAT Akt HIV
Scutellarin, an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts. Scutellarin is active against HIV-1IIIB, HIV-1(74V) and HIV-1KM018 with EC₅₀s of 26 μM, 253 μM and 136 μM, respectively.

Scutellarin (Standard)	Structural Classification Flavonoids Flavones Labiatae Source classification Phenols Polyphenols Plants Medicago truncatula Gaertn.	STAT Akt HIV
Scutellarin (Standard) is the analytical standard of Scutellarin. This product is intended for research and analytical applications. Scutellarin, an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts. Scutellarin is active against HIV-1IIIB, HIV-1(74V) and HIV-1KM018 with EC₅₀s of 26 μM, 253 μM and 136 μM, respectively.

Baicalein 7-O-β-D-ethylglucuronide	Structural Classification Flavonoids Flavones Labiatae Source classification Plants Medicago truncatula Gaertn.	Others
Baicalein 7-O-β-D-ethylglucuronide is a natural flavone glycoside that can be extracted from Scutellaria baicalensis Georgi. Baicalein 7-O-β-D-ethylglucuronide has antioxidant activity. Baicalein 7-O-β-D-ethylglucuronide inhibits FeSO₄-Cys-induced lipid peroxidation of liver homogenate. Baicalein 7-O-β-D-ethylglucuronide also shows strong cytoprotective effect on H₂O₂-induced oxidative damage of human umbilical vein endothelial cells .

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