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Sodium Valproate-d<sub>14</sub>

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Autophagy (1) Endogenous Metabolite (1) HDAC (1) HIV (1) Isotope-Labeled Compounds (1) Mitophagy (1) Notch (1)
By Research Areas:	Cancer (1)

Targets Recommended: Sodium Channel Apical Sodium-Dependent Bile Acid Transporter Na+/H+ Exchanger (NHE) SGLT Na+/K+ ATPase P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-10585AS1

Valproic acid-d14 sodium Sodium Valproate-d<sub>14sub> Sodium	Isotope-Labeled Compounds HDAC Autophagy Mitophagy HIV Notch Endogenous Metabolite	Cancer
Valproic acid-d₁₄ (sodium) is deuterium labeled Valproic acid (sodium). Valproic acid sodium salt (Sodium Valproate) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium salt activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches.

Cat. No.	Product Name	Chemical Structure

HY-10585AS1

Valproic acid-d14 sodium
Valproic acid-d₁₄ (sodium) is deuterium labeled Valproic acid (sodium). Valproic acid sodium salt (Sodium Valproate) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium salt activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches.

Valproic acid-d14 sodium

Valproic acid-d₁₄ (sodium) is deuterium labeled Valproic acid (sodium). Valproic acid sodium salt (Sodium Valproate) is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium salt activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches.

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Sodium Valproate-d<sub>14</sub>

Inhibitors & Agonists

Isotope-Labeled Compounds