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SpCas9

" in MedChemExpress (MCE) Product Catalog:

By Targets:	CRISPR/Cas9 (2)
By Research Areas:	Infection (1)

3

Inhibitors & Agonists

3

Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

BRD0539	CRISPR/Cas9	Infection
BRD0539 is a cell-permeable and non-toxic inhibitor of *CRISPR-Cas9. BRD0539 inhibits Streptococcus pyogenes* Cas9 (SpCas9) (apparent IC₅₀=22 μM) in an in vitro DNA cleavage assay .

BRD7586	CRISPR/Cas9	Others
BRD7586 is a cell-permeable small-molecule inhibitor of *SpCas9*. BRD7586 is the smallest known anti-CRISPR .

SpCas9 D10A Nickase	Others	Others
SpCas9 D10A Nickase is a mutant of the Cas9 protein. SpCas9 D10A Nickase retains the function of a cleavage domain of Cas9 nuclease and specifically cleaves the target single strand to form a nick. SpCas9 D10A Nickase reduces off-target effects .

Tag:	His (2) Tag Free (1)
Source:	E. coli (3)

Cat. No.	Compare	Product Name	Species	Source

	CRISPR-Cas9 Protein, S. pyogenes (His) CRISPR-associated endonuclease Cas9/Csn1; cas9; SpCas9; SpyCas9	Others	E. coli
	The CRISPR-Cas9 protein is part of an immune system that defends against genetic elements. It processes RNA and aids in cleaving DNA targets. Protein and guide RNAs are necessary for its function. The protein recognizes specific sequences to distinguish self from nonself and provides immunity against matching genetic elements. CRISPR-Cas9 Protein, S. pyogenes (His) is the recombinant CRISPR-Cas9 protein, expressed by E. coli , with His tagged. The total length of CRISPR-Cas9 Protein, S. pyogenes (His) is 1367 a.a., with molecular weight of ~163 kDa.

	CRISPR-Cas9 Protein, S. pyogenes (NLS) CRISPR-associated endonuclease Cas9/Csn1; cas9; SpCas9; SpyCas9	Others	E. coli
	The CRISPR-Cas9 protein is part of an immune system that defends against genetic elements. It processes RNA and aids in cleaving DNA targets. Protein and guide RNAs are necessary for its function. The protein recognizes specific sequences to distinguish self from nonself and provides immunity against matching genetic elements. CRISPR-Cas9 Protein, S. pyogenes (NLS) is the recombinant CRISPR-Cas9 protein, expressed by E. coli , with tag free. The total length of CRISPR-Cas9 Protein, S. pyogenes (NLS) is 1368 a.a., with molecular weight of ~160 kDa.

	GMP-CRISPR-Cas9 Protein, S. pyogenes (His) CRISPR-associated endonuclease Cas9/Csn1; cas9; SpCas9; SpyCas9	Others	E. coli
	The CRISPR-Cas9 protein is part of an immune system that defends against genetic elements. It processes RNA and aids in cleaving DNA targets. Protein and guide RNAs are necessary for its function. The protein recognizes specific sequences to distinguish self from nonself and provides immunity against matching genetic elements. GMP-CRISPR-Cas9 Protein, S. pyogenes (His) is the recombinant GMP-CRISPR-Cas9 protein, expressed by E. coli , with His labeled tag. The total length of GMP-CRISPR-Cas9 Protein, S. pyogenes (His) is 1367 a.a., with molecular weight of ~163 kDa.

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