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TIP48/49-IN-1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-103702
    TIP48/49-IN-1

    		Proton Pump Cancer
    TIP48/49-IN-1 (Compound B) is an orally active and specific inhibitor of RUVBL1/2 ATPase, with an IC50 of 59 nM for purified RUVBL1/2. TIP48/49-IN-1 affects DNA replication process, and leads to S-phase arrest. TIP48/49-IN-1 induces apoptosis. TIP48/49-IN-1 inhibits tumor growth and radiosensitizes non-small cell lung cancer cells (NSCLC) .
    TIP48/49-IN-1

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