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Results for "

TPX2

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Recombinant Proteins

2

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-125956
    Aurkin A

    		Aurora Kinase Cancer
    Aurkin A is an allosteric inhibitor for the interaction between Aurora A Kinase (also known also Aurka) and TPX2, through targeting the TPX2 binding sites with Kd of 3.77 μM .
    Aurkin A
  • HY-168022
    CAM2602

    		Aurora Kinase Cancer
    CAM2602 is an Aurora A-TPX2 interaction inhibitor that has a binding affinity of 19 nM to Aurora A. CAM2602 can inhibit the growth of pancreatic cancer cells. In solid tumor transplant models, CAM2602 can increase the proportion of PH3 positive cells while reducing the proportion of P-Thr288 Aurora A positive cells, thereby inhibiting tumor growth .
    CAM2602
  • HY-RS14959
    TPX2 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    TPX2 Human Pre-designed siRNA Set A contains three designed siRNAs for TPX2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    TPX2 Human Pre-designed siRNA Set A
    TPX2 Human Pre-designed siRNA Set A
  • HY-158038
    AurkA allosteric-IN-1

    		Aurora Kinase Cancer
    AurkA allosteric-IN-1 (compound 6h) is an Aurora A (AurkA) inhibitor (IC50: 6.50 μM) that inhibits the catalytic activity and non-catalytic functions of Aurora A. Aurora A regulates the assembly of the bipolar mitotic spindle and the fidelity of chromosome segregation during mitosis and has non-catalytic functions. AurkA allosteric-IN-1 blocks the interaction of AurkA with the activator TPX2 by binding to the Y pocket of AurkA .
    AurkA allosteric-IN-1

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