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Thiocolchicine

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (2) Isotope-Labeled Compounds (1) Microtubule/Tubulin (2)
By Research Areas:	Cancer (2)

Inhibitors & Agonists

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-116852

*Thiocolchicine*	Microtubule/Tubulin Apoptosis	Cancer
Thiocolchicine, a derivative modified in the C Ring of Colchicine (HY-16569) with enhanced biological properties. Thiocolchicine is a potent inhibitor of tubulin polymerization (IC₅₀=2.5 μM) and competitively binds to tubulin with a K_i of 0.7 μM. Thiocolchicine induces cell apoptosis . Thiocolchicine can be used as an ADC cytotoxin in ADC technology.

HY-116852S

Thiocolchicine-d3	Microtubule/Tubulin Apoptosis	Cancer
Thiocolchicine-d₃ is deuterium labeled Thiocolchicine. Thiocolchicine, a derivative modified in the C Ring of Colchicine (HY-16569) with enhanced biological properties. Thiocolchicine is a potent inhibitor of tubulin polymerization (IC50=2.5 µM) and competitively binds to tubulin with a Ki of 0.7 µM. Thiocolchicine induces cell apoptosis[1][2]. Thiocolchicine can be used as an ADC cytotoxin in ADC technology.

HY-132644S1

*3-Demethyl Thiocolchicine--13C2,d6*	Isotope-Labeled Compounds	Others
3-Demethyl Thiocolchicine--- ¹³C₂,d₆ is ¹³C and deuterated labeled 3-Demethyl Thiocolchicine-.

Cat. No.	Product Name	Chemical Structure

HY-116852S

Thiocolchicine-d3
Thiocolchicine-d₃ is deuterium labeled Thiocolchicine. Thiocolchicine, a derivative modified in the C Ring of Colchicine (HY-16569) with enhanced biological properties. Thiocolchicine is a potent inhibitor of tubulin polymerization (IC50=2.5 µM) and competitively binds to tubulin with a Ki of 0.7 µM. Thiocolchicine induces cell apoptosis[1][2]. Thiocolchicine can be used as an ADC cytotoxin in ADC technology.

Thiocolchicine-d3

Thiocolchicine-d₃ is deuterium labeled Thiocolchicine. Thiocolchicine, a derivative modified in the C Ring of Colchicine (HY-16569) with enhanced biological properties. Thiocolchicine is a potent inhibitor of tubulin polymerization (IC50=2.5 µM) and competitively binds to tubulin with a Ki of 0.7 µM. Thiocolchicine induces cell apoptosis[1][2]. Thiocolchicine can be used as an ADC cytotoxin in ADC technology.

HY-132644S1

*3-Demethyl Thiocolchicine--13C2,d6*
3-Demethyl Thiocolchicine--- ¹³C₂,d₆ is ¹³C and deuterated labeled 3-Demethyl Thiocolchicine-.

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