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Results for "

Tizoxanide

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-12687
    Tizoxanide
    5+ Cited Publications

    TIZ

    		 Bacterial HIV Autophagy Parasite IKK Influenza Virus Infection Cancer
    Tizoxanide (TIZ) is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide (TIZ) has anti-HIV-1 activities and potent inhibition of both HBV and HCV replication with values EC50 of 0.46μM and 0.15 μM, respectively. Tizoxanide also exerts anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines and suppressing of the activation of the NF-κB and the MAPK signaling pathways in LPS-treated macrophage cells .
    Tizoxanide
  • HY-12687S
    Tizoxanide-d4

    		Isotope-Labeled Compounds Bacterial HIV Autophagy Infection
    Tizoxanide-d4 is the deuterium labeled Tizoxanide. Tizoxanide is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide has anti-HIV-1 activities[1][2].
    Tizoxanide-d4
  • HY-136307S
    Tizoxanide-d4 glucuronide

    		Parasite Infection
    Tizoxanide-d4 glucuronide is the deuterium labeled Tizoxanide glucuronide. Tizoxanide glucuronide is the metabolite of Nitazoxanide (HY-B0217) and is cell-permeable to inhibit asexual and sexual stages development of parasite C. parvum[1].
    Tizoxanide-d4 glucuronide
  • HY-12687R
    Tizoxanide (Standard)

    TIZ (Standard)

    		 Bacterial HIV Autophagy Parasite IKK Influenza Virus Infection Cancer
    Tizoxanide (Standard) is the analytical standard of Tizoxanide. This product is intended for research and analytical applications. Tizoxanide (TIZ) is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide (TIZ) has anti-HIV-1 activities and potent inhibition of both HBV and HCV replication with values EC50 of 0.46μM and 0.15 μM, respectively. Tizoxanide also exerts anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines and suppressing of the activation of the NF-κB and the MAPK signaling pathways in LPS-treated macrophage cells .
    Tizoxanide (Standard)

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