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Tubulin/HDAC-IN-3

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-149578
    Tubulin/HDAC-IN-3

    		Microtubule/Tubulin HDAC Cancer
    Tubulin/HDAC-IN-3 (compound 12a) is a potent tubulin/HDAC dual inhibitor. Tubulin/HDAC-IN-3 effectively disrupts tubulin polymerization (IC50: 5.4 μM). Tubulin/HDAC-IN-3 exhibits potent HDAC1/8 inhibitory activities, with IC50 values of 0.155 and 0.177 μM, respectively. Tubulin/HDAC-IN-3 works through blocking cellular cycle, inducing apoptosis and inhibiting colony formation .
    Tubulin/HDAC-IN-3

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