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Results for "

USP21

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

3

Recombinant Proteins

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-153045A

    Deubiquitinase Cancer
    BAY-728 can be used as a negative control of BAY-805. BAY-805 is a potent and selective Inhibitor of USP21 .
    BAY-728
  • HY-153045

    Deubiquitinase Cancer
    BAY-805 is a selective inhibitor of ubiquitin-specific protease USP21. BAY-805 has high selectivity for deubiquitinating enzyme (DUB) targets, kinases, proteases and other common target enzymes .
    BAY-805
  • HY-13453
    BAY 11-7082
    305+ Cited Publications

    BAY 11-7821

    IKK Deubiquitinase Autophagy Apoptosis NF-κB Inflammation/Immunology Cancer
    BAY 11-7082 is an IκBα phosphorylation and NF-κB inhibitor. BAY 11-7082 selectively and irreversibly inhibits the TNF-α-induced phosphorylation of IκB-α, and decreases NF-κB and expression of adhesion molecules. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 (IC50=0.19, 0.96 μM, respectively). BAY 11-7082 inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells .
    BAY 11-7082
  • HY-RS15532

    Small Interfering RNA (siRNA) Others

    USP21 Human Pre-designed siRNA Set A contains three designed siRNAs for USP21 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    USP21 Human Pre-designed siRNA Set A
    USP21 Human Pre-designed siRNA Set A
  • HY-158439

    JAK STAT Cancer
    anti-TNBC agent-7 (Compound 13c) possesses anticancer activity, serving as a molecular probe to recognize and regulate the signal transduction of the USP21/JAK2/STAT3 axis, exhibiting nanomolar-level cytotoxicity against MDA-MB-231 and HCC-1806 cancer cells, effectively combating triple-negative breast cancer (TNBC) .
    anti-TNBC agent-7

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